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Generative Language Model for Antibody Sequence Design (IgLM)

Unmet NeedMonoclonal antibody therapies have become an extremely popular and effective treatment route for cancer, rheumatoid arthritis, and infectious diseases. At present, there are over 100 FDA approved monoclonal antibody therapies with many more in late stage clinical trials (see Nature). One approach that is commonly used to generate monoclonal...

Published: 4/24/2026 | Inventor(s): Jeffrey Gray, Jeffrey Ruffolo, Richard Shuai

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Therapeutic Modalities > Antibodies, Copyright

Multiple-instance Learning on Antibody Repertoires for Detecting Specific Antibodies and Paratopes

Unmet NeedAntibodies are one of the most important tools in medicine. Although they have long been essential components of research experiments and diagnostic assays, their use as therapeutics is revolutionizing the treatment of many autoimmune and cancerous conditions. The antibody drug market is estimated at $126.7 billion (BCC Research) and the antibody...

Published: 4/24/2026 | Inventor(s): Jeremias Sulam, Jeffrey Ruffolo, Jeffrey Gray

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Biomarkers