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Rare HOXB13 African Ancestry-specific Gene Mutation: A Promising Prostate Cancer (PCa) Susceptibility Biomarker

Value PropositionIncorporation of the X285K variant of the HOXB13 gene for screening diagnosis or targeted drug discovery will identify and target early-onset and more aggressive prostate cancer disease in higher risk populations. No other HOXB13 variant has been found to be preferentially associated with risk for aggressive prostate cancer, making...

Published: 6/27/2025 | Inventor(s): William Isaacs, Jun Luo, Mayuko Kanayama

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Category(s): Clinical and Disease Specializations > Research Tools > Assays, Clinical and Disease Specializations > Urology