Search Results - jun+luo

3 Results

Sort By:

Rare HOXB13 African Ancestry-specific Gene Mutation: A Promising Prostate Cancer (PCa) Susceptibility Biomarker

Value PropositionIncorporation of the X285K variant of the HOXB13 gene for screening diagnosis or targeted drug discovery will identify and target early-onset and more aggressive prostate cancer disease in higher risk populations. No other HOXB13 variant has been found to be preferentially associated with risk for aggressive prostate cancer, making...

Published: 9/12/2025 | Inventor(s): William Isaacs, Jun Luo, Mayuko Kanayama

Keywords(s):

Category(s): Clinical and Disease Specializations > Research Tools > Assays, Clinical and Disease Specializations > Urology

Androgen Receptor and AR-V7 Knock-out Lines from the LNCaP95 Cell Line

Unmet NeedProstate cancer is considered the most common type of cancer in men with approximately 249,000 new cases and an estimated 34,130 deaths in 2021 (see ACS). Prostate cancer treatment is dependent on tumor staging with early stage intervention including surgery or radiotherapy and later stage management by androgen deprivation therapy (see Uptodate)....

Published: 9/12/2025 | Inventor(s): Jun Luo, Yezi Zhu, Changxue Lu

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Research Tools > Cell Lines

RNA In Situ Hybridization Assay (RISH) for the Detection of Prostate Cancer Cells in Urine

Unmet NeedProstate cancer is one of the most commonly diagnosed cancers in the male population; roughly one out of ten men will be diagnosed at some point in their lives. Efficient screening and accurate diagnosis is a public health imperative due to the large potential patient population. Prostate cancer is usually diagnosed following an abnormal physical...

Published: 9/12/2025 | Inventor(s): Jun Luo, Christian Pavlovich, William Isaacs, Jillian Eskra

Keywords(s): Assay, Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics (Old), Prostate Cancer, Risk Stratification

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Diagnostics > Diagnostic Biomarkers