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SPARC/osteonectin is a Frequent Target for Aberrant Methylation in Pancreatic Adenocarcinoma

C04245: SPARC/osteonectin is a Frequent Target for Aberrant Methylation in Pancreatic Adenocarcinoma Technical Details: Deregulated expression of SPARC/osteonectin, a secreted glycoprotein with multiple biological functions, has been associated with the progression of various cancers. Using microarrays, we previously identified SPARC as one of the...

Published: 3/13/2025 | Inventor(s): Norihiro Sato, Michael Goggins

Keywords(s): Adenocarcinoma, Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Pancreatic Cancer, Pancreatic ductal adenocarcinoma, Pancreatic Ductal Adenocarcinoma

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Adenocarcinoma, Clinical and Disease Specializations > Oncology > Pancreatic Cancer, Clinical and Disease Specializations > Oncology > Pancreatic Ductal Adenocarcinoma, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-throughput Microarrays

C04187: Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-throughput Microarrays Technical Details: In order to identify potential targets for aberrant methylation in pancreatic cancer, we analyzed global changes in gene expression profiles of 4 pancreatic cancer cell lines after treatment with the demethylating...

Published: 3/13/2025 | Inventor(s): Norihiro Sato, Michael Goggins

Keywords(s): Assay, Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Pancreatic Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Pancreatic Cancer, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools