Search Results - retinitis+pigmentosa

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Metipranolol for Treatment of Retinitis Pigmentosa

Unmet NeedRetinitis pigmentosa (RP) is a genetic disorder with a prevalence of 1 in 4000 people worldwide. RP can be the result of a number of mutations that all result in severe rod photoreceptor degeneration and death, causing excess oxygen in the outer retina and subsequent oxidative damage to cone photoreceptors. Symptom onset begins in childhood...

Published: 6/27/2024 | Inventor(s): Peter Campochiaro, Yogita Kanan, Ken Green

Keywords(s): Antagonists/Inhibitors, Disease Indication, Eye Disorders, Macular Degeneration, Non-novel, Predicted Novelty, Repurposed, Retinitis pigmentosa, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Ophthalmology > Retinitis Pigmentosa, Clinical and Disease Specializations > Ophthalmology > Macular Degeneration, Technology Classifications > Therapeutic Modalities > Small Molecules

Drugs Promoting Retinal Rod Photoreceptor Survival

Unmet NeedRetinitis pigmentosa (RP) is a genetic disorder that can result from more than 60 mutations that cause severe rod photoreceptor degeneration and death. It is estimated to affect 1 in 4000 people worldwide, with approximately 100,000 cases in the United States. Symptoms begin in childhood with a loss of night vision, and eventually RP leads...

Published: 6/27/2024 | Inventor(s): Jeff Mumm

Keywords(s): Disease Indication, Eye Disorders, Retinitis pigmentosa, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Therapeutic Modalities > Repurposed Drugs, Technology Classifications > Therapeutic Modalities > Small Molecules