Search Results - robert+johnston

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Novel stem-cell based therapeutic for retinal and macular repair

Unmet Need / Invention Novelty: Currently, there are limited options for patients diagnosed with degenerative macular diseases, with available options reducing the rate of degeneration rather than repairing the diseased retinal tissue. There is an unmet need to develop a novel therapeutic for macular degenerations that repairs diseased tissue. Technical...

Published: 6/28/2024 | Inventor(s): Mandeep Singh, Robert Johnston, Kiara Eldred, Katarzyna Hussey, Sarah Hadyniak, Christina McNerney

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Cell Therapies

Novel universal stem cell-based therapy for the treatment of retinal diseases

Unmet Need / Invention Novelty: Gene augmentation therapy, the current technology for treatment of inherited retinal diseases, is limited by its 1) small cargo capacity which challenges the delivery of larger genes 2) ability to target only a single genetic mutation, and thus disease subtype, at a time, and 3) applicability only to recessive diseases...

Published: 6/28/2024 | Inventor(s): Mandeep Singh, Seth Blackshaw, Robert Johnston, Jiang Qian, Ying Liu

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Cell Therapies