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Generation of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells

Unmet NeedFuchs’ dystrophy, a progressive, hereditary disease of the cornea, is the leading cause of corneal transplants both in the US and worldwide. The disease results in the dysregulation and destruction of corneal endothelial cells which are responsible for keeping the eye properly hydrated. As the disease progresses, patients will experience blurred...

Published: 9/26/2024 | Inventor(s): Sheikh Amer Riazuddin, John Gottsch, Shahid Khan, Muhammad Ali

Keywords(s): Biologics, Cell Therapy, Corneal Dystrophy, Disease Indication, Eye Disorders, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell

Category(s): Clinical and Disease Specializations > Ophthalmology > Corneal Dystrophy, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Research Tools > Research Stem Cells