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High Affinity Nanobodies Specific for Voltage Gated Sodium Channels

Unmet Need Globally, millions of patients are affected by diseases caused when mutations affect the normal function of voltage gated sodium channels (Nav). These mutations have been implicated in several human genetic diseases such as hypokalemic periodic paralysis, myotonia and Brugada syndrome. Myotopic Dystrophy alone affects at least 1 in 8,000...

Published: 3/14/2025 | Inventor(s): Sandra Gabelli, L. Mario Amzel, Lakshmi Srinivasan, Vanina Alzogaray, Manu Ben-Johny

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