Search Results - alan+friedman

2 Results

Sort By:

PSMA Chimeric Antigen Receptor-Modified Proinflammatory Myeloid Cells

Unmet Need: Prostate cancer remains one of the leading causes of cancer-related death among men. Clinical translation of PSMA-CAR-T cell therapies under investigation is hindered by questions as to their tumor infiltration, efficacy, and durability. Immature myeloid cells deficient in the p50-subunit of NF-κB (p50-IMCs) enhance T cell activation. As...

Published: 5/17/2024 | Inventor(s): Alan Friedman

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Cell Therapies

Adoptive Proinflammatory Myeloid Cell Therapy for Cancer

Unmet Need: Prostate cancer is one of the most commonly diagnosed cancers in the male population; roughly one out of ten men will be diagnosed at some point in their lives. Despite extending survival, androgen depravation therapy invariably leads to the development of lethal castration resistant prostate cancer. Similarly, pancreatic ductal carcinoma...

Published: 5/17/2024 | Inventor(s): Alan Friedman

Keywords(s): Biologics, Cancers, Disease Indication, Therapeutic Matter, Therapeutic Substance, Therapeutics, Whole cell

Category(s): Technology Classifications > Therapeutic Modalities > Cell Therapies, Clinical and Disease Specializations > Oncology