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Antimalarial Thioacetal Trioxanes in the Artemisinin Family

C11864: Novel Artemisinin Analog Antimalarial DrugsNovelty: The inventors have created several semisynthetic analogs of artemisinin with antimalarial properties.Value Proposition: In 2010, malaria affected over 216 million people, and while treatments for malaria exist, malaria parasites have grown resistant to several of the commonly used, quinoline-based...

Published: 5/2/2024 | Inventor(s): Alexander Jacobine, Rachel Slack, Jennifer Mazzone, Gary Posner

Keywords(s): Antagonists/Inhibitors, Disease Indication, Infectious Diseases, Malaria, Novel, Parasitic Infections, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Malaria, Clinical and Disease Specializations > Infectious Diseases > Parasitic Infections, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities

Monomeric Trioxane Amide Sulfur Compounds

C11486: Oral Single Dose Therapeutic for MalariaNovelty: The combination of a novel oral drug with Mefloquine administered as a single oral dose demonstrates anti-malarial activity.Value Proposition: Malaria is responsible for a million deaths each year and some treatments are not very effective, as the malarial parasite has developed resistance to...

Published: 5/2/2024 | Inventor(s): Rachel Slack, Gary Posner