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Therapies to Accelerate Resolution of Acute Lung Inflammation

Acute respiratory distress syndrome (ARDS) is a devastating inflammatory lung disease for which there are no effective targeted therapies. In experimental models of acute lung inflammation and injury, regulatory T cells (Tregs) orchestrate a pro-repair program; Tregs themselves are highly dependent on epigenetic mechanisms such as DNA hypomethylation. ...

Published: 3/13/2025 | Inventor(s): Franco D'alessio, Landon King, Benjamin Singer, Neil Aggarwal

Keywords(s): Acute Respiratory Distress Syndrome, Acute Respiratory Distress Syndrome (ARDS), Antagonists/Inhibitors, Chemotherapy, Disease Indication, Immunotherapy, Lung Disorders, Non-novel, Predicted Novelty, Repurposed, Single, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Respiratory Diseases > Acute Respiratory Distress Syndrome, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Therapeutic Modalities > Repurposed Drugs