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Virtual Cortical Stimulation Mapping for Epileptogenic Zone Localization

Unmet NeedCortical stimulation mapping is an electrocorticography monitoring that involves a surgically invasive clinical procedure. Its purpose serves to localize functions of specific cerebral regions of the brain through electrical stimulation of a cerebral cortex. During cortical stimulation mapping, electrodes are placed directly on to the cerebral...

Published: 3/13/2026 | Inventor(s): Sridevi Sarma, Adam Li

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Neurology > Epilepsy

C11355: Therapeutic Alleviating Cognitive Impairment from Multiple Sclerosis (MS)

Novelty:This technology is a first of its kind, potential therapeutic in alleviating cognitive impairment (CI) as a result of Multiple Sclerosis (MS) and related central nervous system (CNS) autoimmune diseases.Value Proposition:CI is a debilitating outcome of many CNS disorders, including MS. Currently, the high prevalence of CI and the extremely negative...

Published: 3/12/2026 | Inventor(s): Barbara Slusher, Kristen Hollinger, Adam Kaplin

Keywords(s): Antagonists/Inhibitors, Biomarker, Clinical Diagnostics, CNS and Neurological Disorders, Cognitive Impairment, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Mechanism of Action Biomarker, Multiple CNS Indications, Non-novel, Predicted Novelty, Repurposed, Small Molecules, Target, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Neurology > Cognitive Impairment, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Technology Classifications > Therapeutic Modalities