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Greater Promoter Methylation and Somatic Mutation Analyses Reveal Alterations in PAX, NOTCH, and TP53 Pathways Associated with Poor Survival in Head and Neck Cancer

Novel Biomarkers for Predicting Head & Neck Cancer RiskC12502Invention Novelty: This invention provides DNA methylation-based biomarkers for predicting Head & Neck Cancer risk. Value Proposition: Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer worldwide with more than 500,000 new cases and 300, 000 deaths each...

Published: 3/13/2025 | Inventor(s): Christina Michailidi, David Sidransky, Rafael Guerrero-Preston

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, Epigenetic, Head & Neck Cancer, Head and Neck Cancer, In Vitro Diagnostics, Methylation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Head & Neck Cancer