Search Results - head+%26+neck+cancer

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Greater Promoter Methylation and Somatic Mutation Analyses Reveal Alterations in PAX, NOTCH, and TP53 Pathways Associated with Poor Survival in Head and Neck Cancer

Novel Biomarkers for Predicting Head & Neck Cancer RiskC12502Invention Novelty: This invention provides DNA methylation-based biomarkers for predicting Head & Neck Cancer risk. Value Proposition: Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer worldwide with more than 500,000 new cases and 300, 000 deaths each...

Published: 3/13/2025 | Inventor(s): Christina Michailidi, David Sidransky, Rafael Guerrero-Preston

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, Epigenetic, Head & Neck Cancer, Head and Neck Cancer, In Vitro Diagnostics, Methylation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Head & Neck Cancer

Nicastrin Knockout Mice: A Model for Human Head and Neck Squamous Cell Carcinoma

C10173: Mouse Model of Human Head and Neck Squamous Cell Carcinoma Technical Details: Cancers of the head and neck, the majority of which arise in the squamous cells that line the mucosal surfaces in the head and neck, account for 3% of all malignancies in the United States. Human head and neck squamous cell carcinoma is a clinically aggressive tumor,...

Published: 3/13/2025 | Inventor(s): Donald Price, Tong Li, Philip Wong

Keywords(s): Basic Research Biomarker, Cancers, Discovery/Research Tools, Disease Indication, Head & Neck Cancer, Head and Neck Cancer, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Head & Neck Cancer, Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools