🔍
Search Results - clinical+and+disease+specializations+%3e+neurology+%3e+cognitive+impairment
5
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Acetylated Polyamines as Biomarkers of HIV-1 Associated Neurocognitive Disorders (HAND)
Acetylated Polyamines as Biomarkers of HIV-1 Associated Neurocognitive Disorders (HAND) Marketing Summary: Polyamines are molecules, present in all organisms, whose concentrations are regulated by the enzyme Spermine/Spermidine Acetyl transferase (SSAT). SSAT works by inactivating polyamines. Once these polyamines are inactivated they are...
Published: 3/13/2025
|
Inventor(s):
Kamel Khalili
,
Carlos Barrero
,
Salim Merali
,
Jay Rappaport
,
Norman Haughey
,
Ned Sacktor
Keywords(s):
Biomarker
,
Clinical Diagnostics
,
CNS and Neurological Disorders
,
Cognitive Impairment
,
Diagnostic Biomarker
,
Disease Indication
,
HIV/AIDS
,
HIV-Associated Neurocognitive Disorders
,
In Vitro Diagnostics
Category(s):
Clinical and Disease Specializations
,
Technology Classifications > Diagnostics > Biomarkers
,
Technology Classifications > Diagnostics > Diagnostic Biomarkers
,
Technology Classifications > Diagnostics > In Vitro Diagnostics
,
Technology Classifications > Diagnostics
,
Clinical and Disease Specializations > Infectious Diseases
,
Clinical and Disease Specializations > Neurology
,
Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS
,
Clinical and Disease Specializations > Neurology > Cognitive Impairment
,
Clinical and Disease Specializations > Neurology > HIV-Associated Neurocognitive Disorders
Machine Learning Algorithm for Delirium Prediction in the Intensive Care Unit
Unmet NeedDelirium is a potentially preventable and often reversible disorder of impaired cognition. It is common in the intensive care unit (ICU), with an overall prevalence of 32.3%. However, the prevalence is dependent on the type of patients. For example, among ventilated burn patients, the prevalence is 77%, and among mechanically ventilated patients,...
Published: 3/14/2025
|
Inventor(s):
Robert Stevens
,
Kirby Gong
,
Akaash Sanyal
,
Joanna Guo
,
Ryan Lu
,
Teya Bergamaschi
,
Han Kim
Keywords(s):
Category(s):
Clinical and Disease Specializations > Neurology > Dementia
,
Clinical and Disease Specializations > Neurology > Cognitive Impairment
,
Clinical and Disease Specializations > Neurology
,
Technology Classifications > Computers, Electronics & Software > Algorithms
,
Technology Classifications > Computers, Electronics & Software > Artificial Intelligence
,
Technology Classifications > Computers, Electronics & Software > Machine Learning
,
Technology Classifications > Diagnostics > Prognostic Biomarkers
Smartphone-Based Head Impulse Nystagmus Test of Skew (HINTS) to Aid the Diagnosis of Patients with Vertigo and Dizziness
Unmet Need:It is estimated that 45,000-75,000 strokes are missed in emergency departments each year in the United States due to patients presenting with dizziness. Of these patients, 15,000-25,000 will have a subsequent major stroke that could’ve been prevented with earlier identification and treatment. These strokes are often missed due to the fact...
Published: 3/14/2025
|
Inventor(s):
David Newman-Toker
,
Jorge Otero-Millan
,
Nathan Farrell
,
Taylor Parker
Keywords(s):
Clinical Diagnostics
,
Diagnostic Tool
,
Screening Questionnaire
Category(s):
Technology Classifications > Computers, Electronics & Software > Clinical Management
,
Technology Classifications > Diagnostics
,
Clinical and Disease Specializations > Neurology > Cognitive Impairment
Glutamine Antagonists for the Treatment of Cognitive Deficits, including NeuroAIDs
Some glutamine antagonists have been shown to have anti-cancer activities in multiple preclinical and clinical studies. However the toxicity of the glutamine antagonists at doses necessary for their anticancer effects have hampered their clinical development. Herein we describe a completely novel use for the glutamine antagonists. Using a prototype...
Published: 3/13/2025
|
Inventor(s):
Barbara Slusher
,
David Volsky
,
Kristen Hollinger
,
Michael Nedelcovych
,
Atsushi Kamiya
Keywords(s):
Antagonists/Inhibitors
,
CNS and Neurological Disorders
,
Cognitive Impairment
,
Disease Indication
,
HIV/AIDS
,
HIV-Associated Neurocognitive Disorders
,
Non-novel
,
Predicted Novelty
,
Repurposed
,
Small Molecules
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS
,
Clinical and Disease Specializations > Neurology > Cognitive Impairment
,
Clinical and Disease Specializations > Neurology > HIV-Associated Neurocognitive Disorders
,
Technology Classifications > Therapeutic Modalities > Small Molecules
,
Clinical and Disease Specializations > Infectious Diseases
,
Clinical and Disease Specializations > Neurology
,
Technology Classifications > Therapeutic Modalities
C11355: Therapeutic Alleviating Cognitive Impairment from Multiple Sclerosis (MS)
Novelty:This technology is a first of its kind, potential therapeutic in alleviating cognitive impairment (CI) as a result of Multiple Sclerosis (MS) and related central nervous system (CNS) autoimmune diseases.Value Proposition:CI is a debilitating outcome of many CNS disorders, including MS. Currently, the high prevalence of CI and the extremely negative...
Published: 3/13/2025
|
Inventor(s):
Barbara Slusher
,
Kristen Hollinger
,
Adam Kaplin
Keywords(s):
Antagonists/Inhibitors
,
Biomarker
,
Clinical Diagnostics
,
CNS and Neurological Disorders
,
Cognitive Impairment
,
Diagnostic Biomarker
,
Disease Indication
,
In Vitro Diagnostics
,
Mechanism of Action Biomarker
,
Multiple CNS Indications
,
Non-novel
,
Predicted Novelty
,
Repurposed
,
Small Molecules
,
Target
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Neurology
,
Clinical and Disease Specializations > Neurology > Cognitive Impairment
,
Technology Classifications > Diagnostics > Biomarkers
,
Technology Classifications > Diagnostics > Diagnostic Biomarkers
,
Technology Classifications > Diagnostics > In Vitro Diagnostics
,
Technology Classifications > Therapeutic Modalities > Small Molecules
,
Technology Classifications > Therapeutic Modalities > Targets
,
Technology Classifications > Diagnostics
,
Technology Classifications > Therapeutic Modalities
JHTV Home
|
Search
|
Login/Subscribe
2017 - 2022 © Johns Hopkins Technology Ventures. All Rights Reserved. Powered by
Inteum