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Identification of LAG3 as the α-synuclein Neuronal Transmission Receptor
Unmet Need: Parkinson’s disease (PD) is the second most common neurodegenerative disorder and leads to slowness of movement, tremor, rigidity, and, in the later stages of PD, cognitive impairment. Pathologically, PD is characterized by the accumulation of α-synuclein in Lewy bodies and neurites. Emerging evidence indicates that the pathogenesis of Parkinson's...
Published: 3/13/2025
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Inventor(s):
Ted Dawson
,
Valina Dawson
,
Han Seok Ko
,
Xiaobo Mao
,
Dario Vignali
,
Creg Workman
Keywords(s):
Biomarker
,
CNS and Neurological Disorders
,
Disease Indication
,
Mechanism-of-action Biomarker
,
Parkinson's Disease
,
Therapeutic Matter
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Neurology > Parkinson's Disease
,
Technology Classifications > Diagnostics > Biomarkers
,
Technology Classifications > Therapeutic Modalities > Targets
,
Technology Classifications > Diagnostics
,
Clinical and Disease Specializations > Neurology
,
Technology Classifications > Therapeutic Modalities
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