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Oxygen Gradient Hydrogels to Study and Screen Potential Cancer Therapeutics

Unmet needHypoxia is a critical factor in the progression and metastasis of many cancers. Frequently, oxygen gradients develop in tumors as they grow beyond their vascular supply leading to heterogeneous areas of oxygen depletion.Technology OverviewJohns Hopkins researchers have created a gradient hydrogel (collagen and gelatin) and observed that hypoxic...

Published: 3/13/2025 | Inventor(s): Sharon Gerecht, Daniel Lewis, Kyung Min Park, Tzipora Sarah Eisinger, M. Simon

Keywords(s): Cancers, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Target-based Screening Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools, Technology Classifications > Diagnostics