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Peptide-Based Antifouling Membrane Filtration Systems for Continuous Protein Harvesting
Unmet NeedCell and cell-derived therapies, including protein and antibodies, are being developed as a new and promising class of medicine. These kinds of therapeutics require a nuanced and precise manufacturing process, including bioreactors and filtration systems that can reliably obtain large quantities of the desired product consistently [8, 9]....
Published: 3/14/2025
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Inventor(s):
Honggang Cui
,
Boran Sun
,
Michael Betenbaugh
,
David Stern
Keywords(s):
Category(s):
Polymers for Binding-Triggered Antibody Precipitation and Purification
Value PropositionResults in >97% precipitation yield, >88% elution yield of mAbsSimplified molecular design compared to elastin-like polypeptide (ELP)-based materialsDoes not need additional salt to achieve mAb precipitation and recoveryTechnology DescriptionResearchers at Johns Hopkins have developed a peptide-based platform technology using...
Published: 3/14/2025
|
Inventor(s):
Honggang Cui
,
Yi Li
,
David Stern
,
XuanKuo Xu
,
Lye Lin Lock
,
Jason Mills
,
Sanchayita Ghose
,
Zheng Jian Li
Keywords(s):
Category(s):
Clinical and Disease Specializations > Immunology
,
Clinical and Disease Specializations > Research Tools
,
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Research Antibodies
,
Technology Classifications > Therapeutic Modalities > Antibodies
,
Technology Classifications > Therapeutic Modalities > Therapeutic Antibodies
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