Search Results - eduardo+marban

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Modulation of Bio-electrical Rhythms Via a Novel Engineering Approach

Spontaneous cellular electrical rhythms govern numerous biological processes from the autonomous beating of the heart, to respiratory rhythms and insulin secretion. For instance, abnormal pacing in the heart leads to various forms of electrical disorders that necessitate conventional pharmacologic interventions and implantation of costly electronic...

Published: 3/13/2025 | Inventor(s): Hee Cheol Cho, Tian Xue, Eduardo Marban, Suk-Ying Tsang, Ronald Li

Keywords(s): Biologics, Gene Therapy, Nucleic Acid, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities

Combined Multi-detector CT Angiography and CT Myocardial Perfusion Imaging for the Diagnosis of Coronary Artery Disease

C05074: Coronary Artery Disease ScanNovelty: A new imaging study that gives detailed diagnostic information for Coronary Artery Disease.Value Proposition: The diagnosis of Coronary Artery Disease (CAD) is commonly performed through imaging studies. Myocardial perfusion imaging (MPI) uses single photon emission tomography to assess the physiological...

Published: 3/13/2025 | Inventor(s): Joao A. C. Lima, Eduardo Marban, Takashi Ichihara, Richard George, Albert Lardo

Keywords(s): Cardiovascular Diseases, Coronary Heart Disease, Disease Indication, Image Display Software, Image Processing Hardware, Image Processing Software, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, X-ray Computed Tomography (CT), X-Ray Computed Tomography (CT)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Coronary Heart Disease, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices

Genetic Calcium Channel Blocking Therapy

C04144: Genetic Calcium Channel Blocking TherapyNovelty: This technology involves genetic therapy for focal modulation of calcium channel activity, effectively preventing, treating and reducing the severity of many calcium channel related disorders.Value Proposition: Calcium channels are vital for normal functions of many biological processes however,...

Published: 3/13/2025 | Inventor(s): Mitsushige Murata, Eduardo Marban

Keywords(s): Biologics, Gene Therapy, Nucleic Acid, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Cardiovascular

Enhanced and Effective Gene Therapy Delivery Method

C03765: Enhanced and Effective Gene Therapy Delivery MethodNovelty: This technology is an effective gene delivery system that enhances gene transfer and expression to a solid mass of cells, particularly a solid organ, while resulting in minimal degradation and injury to endothelial cells.Value Proposition: Effective delivery of nucleic acids to desired...

Published: 3/13/2025 | Inventor(s): Koichi Nagata, Eduardo Marban, John Lawrence, J. Donahue

Keywords(s): Drug Delivery Vehicle, Gene Therapy, Single, Therapeutic Matter, Therapeutics, Therapy Type

Category(s): Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities

Neuroprotection and Inhibition of Apoptosis by Mitrochondrial Potassium Channel Openers

C03742: Neuroprotection and Inhibition of Apoptosis by Mitrochondrial Potassium Channel Openers Technical Details: Mitochondria can either enhance or suppress cell death. Cytochrome C release triggers apoptosis, but activation of mitochondrial ATP-sensitive potassium (mitoPotassiumATP) channels prevents lethal ischemic injury in vivo. To clarify the...

Published: 3/13/2025 | Inventor(s): Brian O'rourke, Eduardo Marban

Keywords(s): Biomarker, Cardiovascular Diseases, CNS and Neurological Disorders, Disease Indication, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Clinical and Disease Specializations > Neurology, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Technology Classifications > Therapeutic Modalities