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Nucleoside-modified mRNA-lipid nanoparticle lineage vaccine for Hepatitic C
Value Proposition· Compositions for inducing anti-HCV immune responses · Nucleoside-modified RNA encoding one or more HCV antigens to induce robust preventive or therapeutic adaptive immune responses against HCV Unmet Need· Hepatitis C virus (HCV) infection remains a significant clinical burden and is the leading cause of liver transplantation...
Published: 3/14/2025
|
Inventor(s):
Justin Bailey
,
Stuart Ray
,
James Crowe
,
Andrew Flyak
,
George Shaw
,
Drew Weissman
Keywords(s):
Category(s):
Technology Classifications > Diagnostics
Hepatitis C virus E1E2 genes stimulating development of broadly neutralizing antibodies
Unmet Need185 million people worldwide are infected with Hepatitis C (HCV). It is a major cause of liver failure and hepatocellular carcinoma. Recent development of potent, oral, interferon-free therapies have improved treatment of HCV significantly, but treatment alone is unlikely to eradicate the disease. There remain the issues of therapy being costly,...
Published: 3/13/2025
|
Inventor(s):
Justin Bailey
,
James Crowe
,
Andrew Flyak
,
George Shaw
,
Stuart Ray
Keywords(s):
Biologics
,
Disease Indication
,
Hepatitis C Virus
,
Hepatitis C Virus (HCV)
,
Infectious Diseases
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
,
Vaccine
,
Viral Infections
Category(s):
Clinical and Disease Specializations
,
Technology Classifications > Therapeutic Modalities > Biologics
,
Technology Classifications > Therapeutic Modalities > Vaccines
,
Clinical and Disease Specializations > Infectious Diseases
,
Technology Classifications > Therapeutic Modalities
,
Clinical and Disease Specializations > Infectious Diseases > Hepatitis C Virus
,
Clinical and Disease Specializations > Infectious Diseases > Viral Infections
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