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Lead Indole-2-carboxyamide Derivative Compounds for Treatment of TB

Unmet NeedAlthough effective therapy exists for TB caused by drug-susceptible mycobacterium tuberculosis, this therapy requires daily administration of multiple drugs for a minimum of 6 months. The consequence of noncompliance with the existing TB treatment leads to the development of drug-resistant TB in which case both first-line and second-line drug...

Published: 3/13/2025 | Inventor(s): Shichun Lun, Alan Kozikowski, Jozef Stec, Oluseye Onajole, Haidan Guo, William Bishai

Keywords(s): Antagonists/Inhibitors, Disease Indication, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities