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Antiviral Compositions and Methods of Use

Technical Details: This invention is related to isolation of two highly potent, non-toxic inhibitors against human immunodeficiency virus type 1 (HIV-1) integrase and viral replication. Two water soluble compounds, M522 and M532, have been discovered by isolating them from Salvia miltiorrhiza roots in purities of > 99.5 % as reported by NMR spectral...

Published: 3/13/2025 | Inventor(s): Ibrahim Abd-Elazem, Ru Chih Huang, Hongshan Chen

Keywords(s): Antagonists/Inhibitors, Disease Indication, HIV, HIV/AIDS, Infectious Diseases, Natural compounds, Non-novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Viral Infections

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS, Clinical and Disease Specializations > Infectious Diseases > Viral Infections, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities