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Personalized, Allogeneic Cell Therapy of Cancer

The present invention describes methods of preparing a cell composition for treating cancer in a human being by obtaining lymphocytes from a partially or fully HLA-matched healthy donor, activating and expanding T cells reactive to tumor neoantigens (i.e. new epitopes resulting from somatic mutations in the cancer cell), and enriching for tumor-specific...

Published: 3/13/2025 | Inventor(s): Ephraim Fuchs, Howard Simons

Keywords(s): Biologics, Cancers, Cell Therapy, Disease Indication, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities