Search Results - hua+yu

2 Results

Sort By:

Targeting of Stat-3 Signaling in the Hematopoietic System Evokes Multicomponent Therapeutic Antitumor Immunity

C04665: Targeting of Stat-3 Signaling in the Hematopoietic System Evokes Multicomponent Therapeutic Antitumor Immunity Technical Details: The immune system can act as an extrinsic suppressor of tumors. Therefore, tumor progression depends in part on mechanisms that down modulate intrinsic immune surveillance. Identifying these inhibitory pathways...

Published: 3/13/2025 | Inventor(s): Richard Jove, Hua Yu, Marcin Kortylewski, Drew Pardoll

Keywords(s): Biologics, Cancers, Combination, Disease Indication, Gene Therapy/ Immunotherapy, Protein, Single, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities

Stat3 Antagonists and Their Uses as Vaccines Against Cancer

C04271: Stat3 Antagonists and Their Uses as Vaccines Against Cancer Technical Details: The present invention relates to methods for treating and/or preventing cancer. In particular the present invention relates to ex vivo immunotherapeutic methods. The methods comprise decreasing Stat3 (signal transducer and activator of transcription3) expression...

Published: 3/13/2025 | Inventor(s): Richard Jove, Hua Yu, Drew Pardoll

Keywords(s): Biologics, Cancers, Disease Indication, Immunotherapy, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vaccine

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines