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Arsenic compounds for Hedgehog pathway blockade in proliferative disorders, including hematopoietic malignancies

INVENTION NOVELTYJohns Hopkins researchers have developed a novel Hedgehog signaling pathway inhibitor that can be used in the treatment of various types of leukemia.VALUE PROPOSITIONThe Hedgehog (Hh) pathway has been found to be important in a number of cancers. Various Hh inhibitors, specifically Smo antagonists, are in development or have been launched...

Published: 10/3/2024 | Inventor(s): Jynho Kim, Philip Beachy

Keywords(s): Antagonists/Inhibitors, Cancers, Disease Indication, Non-novel, Predicted Novelty, Single, Small Molecules, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Therapeutic Modalities