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Method for Surface Expression of Membrane Proteins that have a Cytoplasmic C-terminal Tail

Enhanced Vaccine Development through Optimized Antigen DisplayJHU Ref #: C16777Value Proposition· Improved antigenicity due to increased cell surface expression of viral proteins · Boosts vaccine efficacy · Potential for integration into various vaccine platforms, including viral-mediated, mRNA-mediated, and DNA-mediated vaccines Unmet...

Published: 3/14/2025 | Inventor(s): Stephen Gould, Linda Marban, Chenxu Guo, Shang-Jui Tsai

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A p105-based NF-(kappa) B Super repressor

C04290: A p105-based NF-(kappa) B Super repressor Technical Details: Nuclear factor (NF)-kB is a family of transcription factors that regulate immune and inflammatory responses, programmed cell death (apoptosis), and developmental processes. In normal cells, NF-kB is latent, and is activated transiently by stimuli and stresses. However, under pathological...

Published: 3/13/2025 | Inventor(s): Li Lin

Keywords(s): Biologics, Cancers, Chemotherapy, Disease Indication, Nucleic Acid, Single, Skin Cancer, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Dermatology, Clinical and Disease Specializations > Oncology > Skin Cancer, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities