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Enzymes and Methods for Improved Syntheses of Carbapenem Beta-Lactam Antibiotics

Value Proposition:• Regio- and stereospecific introduction of the (8R)-hydroxyl group late in a chemoenzymatic production process• Simpler, more chemically robust starting materials can be used from the outset allowing more vigorous reaction conditions in subsequent steps• Simpler, cheaper, and more robust routs of syntheses of carbapenem Beta-lactam...

Published: 7/23/2026 | Inventor(s): Micah Bodner, Michael Freeman, Ryan Phelan, Craig Townsend

Keywords(s): Disease Indication, Infectious Diseases, Therapeutic Matter, Therapeutic Substance Synthesis Method, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities