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A Method to Conditionally Deliver Effector Proteins to Plasma and Endosomal Membranes in Response to Tyrosine Kinase Signaling

JHU Ref #: C17482Value Proposition· Effective & Targeted: Harnesses endogenous pain signaling via receptor tyrosine kinases to conditionally deliver effector proteins to the plasma membrane, enabling suppression of chronic pain under pathological conditions· Broadly Applicable: Enables modular, tunable therapy tailored to the prevailing...

Published: 6/27/2025 | Inventor(s): Michael Caterina, Stephen Gould, Shang-Jui Tsai

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