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Compositions and Methods for Treating Solid Tumors

UNMET NEEDCancers are now recognized as being driven by widespread changes in the epigenome including changes in DNA methylation and chromatin packaging. Changes in DNA methylation include global loss of methylation and focal gain of methylation at promoter regions of tumor suppressor genes leading to transcriptional silencing. DNA methylation, the...

Published: 6/27/2024 | Inventor(s): Cynthia Zahnow, Stephen Baylin, Michael Topper, Meredith Stone

Keywords(s): Cancers, Chemotherapy/Chemotherapy, Combination, Disease Indication, Therapeutic Matter, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities