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Potent, Simplified Derivatives of Immunosuppressive Agents

C04420: Potent, Simplified Derivatives of Immunosuppressive Agents Technical Details: Pateamine A (PatA), a metabolite from the marine sponge Mycale, is a potent inhibitor of the intracellular signal transduction pathway that emanates from the T-cell receptor and leads to the transcription of cytokines such as interleukin-2 (IL-2). Researchers at...

Published: 3/13/2025 | Inventor(s): Daniel Romo, Nam Song Choi, Zonggao Shi, Jun Liu, Woon-Kai Low, Yongjun Dang, Tilman Schneider-Poetsch

Keywords(s): Antagonists/Inhibitors, Cancers, Disease Indication, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities