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C13826: Quantitative Determination of Nucleoside Analogue Drugs in Genomic DNA or RNA
Unmet Need:Hematologic and epithelial malignancies have been shown to progress by epigenetically silencing genes that code for tumor suppressors, cell cycle regulators or proteins involved in cell-cell interaction. Gene suppression occurs through promoter methylation and modification of histones. Drugs which are able to manipulate promoter methylation...
Published: 3/13/2025
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Inventor(s):
Michelle Rudek-Renaut
,
Srinivasan Yegnasubramanian
,
Nicole Anders
Keywords(s):
Analytical Method
,
Assay
,
Biomarker
,
Cancers
,
Clinical Diagnostics
,
Discovery/Research Tools
,
Disease Indication
,
Epigenetic
,
In Vitro Diagnostics
,
In Vitro Research Tool
,
Methylation
Category(s):
Technology Classifications > Research Tools
,
Clinical and Disease Specializations > Oncology
,
Technology Classifications > Research Tools > Assays
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