Search Results - soichiro+asami

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Methods for in situ Detection of DNA Sequence Variation

Value Proposition· High-throughput· Assess genetic variants with simultaneous spatial analysis· Interrogate over 100 variants in a single assayUnmet Need· Next generation sequencing has led to an ever-proliferating dearth of genetic information. More recent progress in nucleoside tissue analysis has birthed the field of spatial...

Published: 3/14/2025 | Inventor(s): Reza Kalhor, Soichiro Asami

Keywords(s):

Category(s): Technology Classifications, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Bioinformatics, Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Nucleic Acids

Methods for Clearing and Molecular Analysis in Thick Tissue Sections

Unmet Need· Current techniques for in situ transcriptomics (or spatial transcriptomics) are effectively limited to thin tissue sections of approximately 15 microns due to the poor molecular diffusion and opacity of thicker tissues. Consequently, these techniques are unable to resolve spatial variation of transcription in 3D. Thus, there is a need...

Published: 3/14/2025 | Inventor(s): Reza Kalhor, Soichiro Asami

Keywords(s):

Category(s): Technology Classifications > Research Tools > Blood & Tissue Samples, Technology Classifications > Research Tools > Buffers & Media Solutions, Technology Classifications > Research Tools > Specimen Handling, Technology Classifications > Research Tools > Assays