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Multi-MHC Targeting Bispecific Antibody Platform for T-Cell Activation Against HIV-Infected Cells
Value Proposition· Superior target stability: Targets conserved HIV structural protein-derived peptide:MHC complexes that are highly expressed and stable, unlike rapidly-internalizing variable Env proteins used by current bispecifics· Comprehensive MHC coverage: First platform addressing HIV peptides across MHC-I, MHC-II, and HLA-E pathways,...
Published: 1/22/2026
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Inventor(s):
Srona Sengupta
,
Robert Siliciano
,
Scheherazade Sadegh-Nasseri
,
Jacqueline Douglass
Keywords(s):
Category(s):
Clinical and Disease Specializations > Infectious Diseases > HIV
,
Technology Classifications
,
Technology Classifications > Research Tools > Assays
,
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools
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