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Diagnosis of PD and Related α-synucleinopathies through Assessment of and c-Abl Pathway Molecules from Serum or Plasma L1Cam+ Exosomes

Unmet NeedMore than 10 million people worldwide are currently living with Parkinson’s disease (PD), which is a neurodegenerative disorder that affects movement through degeneration of the dopamine-producing (DA) neurons in the brain. The cause of PD is currently unknown, and no specific tests exist to diagnose the disease. Neurologists diagnose PD based...

Published: 3/14/2025 | Inventor(s): Ted Dawson, Liana Rosenthal, Saurav Brahmachari, Tae-In Kam, Valina Dawson

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Category(s): Technology Classifications > Diagnostics > Diagnostic Biomarkers

Detection of PAR for a Diagnosis in the CSF of Parkinson’s Disease (PD) Patients

Unmet Need Parkinson’s disease (PD) is a common neurodegenerative disease characterized by a gradual loss of all motor function. Currently, no diagnostic test exists for PD. Nevertheless, the early diagnosis of PD is critical for successful disease management as pharmacological treatments like levodopa are most effective when administered at the earliest...

Published: 3/13/2025 | Inventor(s): Ted Dawson, Valina Dawson, Tae-In Kam, Liana Rosenthal, Shaida Andrabi

Keywords(s): Assay, Biomarker, Clinical Diagnostics, CNS and Neurological Disorders, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Parkinson's Disease

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools, Clinical and Disease Specializations > Neurology > Parkinson's Disease