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Engineered Fibroblasts as Cell Therapy to Treat Cancer via Tumor Stroma Stabilization

Unmet Need / Invention Novelty: Carcinoma associated fibroblasts (CAFs) are associated with the development of high-grade malignancies of poor prognoses, as they facilitate cancer invasion and hinder anti-cancer drug delivery. In order to improve the long-term survival rate of pre-metastatic cancer patients, we report genetically engineered fibroblasts...

Published: 3/14/2025 | Inventor(s): Yun Chen, Wei-Hung Jung, Michael Betenbaugh, Franck Housseau

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Category(s): Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Therapeutic Modalities > Cell Therapies, Clinical and Disease Specializations > Oncology > Colorectal Cancer