Search Results - yun+chen

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Engineered Fibroblasts as Cell Therapy to Treat Cancer via Tumor Stroma Stabilization

Unmet Need / Invention Novelty: Carcinoma associated fibroblasts (CAFs) are associated with the development of high-grade malignancies of poor prognoses, as they facilitate cancer invasion and hinder anti-cancer drug delivery. In order to improve the long-term survival rate of pre-metastatic cancer patients, we report genetically engineered fibroblasts...

Published: 6/28/2024 | Inventor(s): Yun Chen, Wei-Hung Jung, Michael Betenbaugh, Franck Housseau

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Therapeutic Modalities > Cell Therapies, Clinical and Disease Specializations > Oncology > Colorectal Cancer

Development of force-dependent drug release system for to enhance selective killing and minimize adverse effects in cancer treatment

Unmet NeedEach year, 650,000 people receive chemotherapy in an outpatient oncology clinic in the US. This technology is a development of force-dependent drug release system for the enhancement of selective killing and minimization of adverse effects to cancer treatments. Current chemotherapies suffer drawback: normal cells might be and are often inadvertently...

Published: 6/27/2024 | Inventor(s): Yun Chen, Seungman Park

Keywords(s): Biologics, Cancers, Disease Indication, Drug Delivery Device, Implanted Device, Implants, Protein, Therapeutic Devices, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Proteins, Clinical and Disease Specializations > Oncology