Search Results - implants

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Unmet NeedAortic aneurysms were the cause of almost 10,000 deaths in 2017, and currently have an incidence of 10 cases per 100,000 in the United States. Aortic aneurysms that involve larger vessels pose extremely challenging problems for vascular surgeons. Almost all the vessels that branch out from the aneurysm will require revascularization, but it...

Published: 3/13/2025 | Inventor(s): Andrew Schulick, Devika Singh

Keywords(s): Cardiovascular Diseases, Disease Indication, Implanted Device, Implants, Stent, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular

Cell Impregnated Nanofiber Stent Sleeve ("CINSS") for Intravascular Growth Factor Production

Invention novelty:Stem cells are harnessed to create a stent-based “paracrine factor factory” using a novel biodegradable nanofiber sleeve which protects the cells from washout and immune attack, and provides a sheltered in vivo on-stent milieu for the cells to continuously produce and deliver healing growth factors and exosomes to injured tissue.Value...

Published: 3/13/2025 | Inventor(s): Chao-Wei Hwang, Zhiyong Xia, Virginia Bogdan, Jeffrey Brinker, Gary Gerstenblith, Peter Johnston, Steven Schulman, Gordon Tomaselli, Robert Weiss

Keywords(s): Drug Delivery Vehicle, Hydrogel, Implanted Device, Implants, Stent, Therapeutic Devices, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities

Artificial Corneal Device

Unmet NeedCorneal blindness affects an estimated 10 million people worldwide, particularly prevalent in the underdeveloped world. Currently, only about 10% of patients receive a corneal transplant due to a shortage of human donor corneas and difficulty in preserving the tissues. Meanwhile, even in countries with a sufficient donor supply, some patients...

Published: 3/14/2025 | Inventor(s): Esen Akpek, Gopalan Balaji, Thomas Schmiedel, Anuraag Singh

Keywords(s): Carriers/Appliers, Disease Indication, Eye Disorders, Implantation Method, Implants, Interventional and Surgical Systems, Surgical Instruments, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Ophthalmology

Implantable lens capsule for intraocular lens insertion.

Unmet NeedCataract surgery is the most common intraocular surgery, with more than 3.5 million occurring each year in the U.S. Various circumstances compromise the ability to safely insert an intraocular lens (IOL) implant following cataract extraction such as zonular insufficiency or posterior capsule rupture. Alternatives for IOL placement within the...

Published: 3/13/2025 | Inventor(s): Albert Jun, Angela Zhu, Peter Gehlbach

Keywords(s): Disease Indication, Eye Disorders, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

Safe Direct Current Stimulator Design for Reduced Power and Increased Reliability

Unmet NeedNeuroprostheses, such as cochlear implants and neural pacemakers, have already been proven to be useful in varying applications. Current neuroprostheses tools typically employ biphasic pulsatile stimulation, a process where electrodes have both a cathodic phase and an anodic phase to pass charge in both directions. Direct current (DC) has...

Published: 3/13/2025 | Inventor(s): Gene Fridman

Keywords(s): CNS and Neurological Disorders, Computer and Network Systems, Computer Hardware, Disease Indication, Implanted Device, Implants, Neuromodulator, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

COMPOSITIONS AND METHODS FOR PREPARATION OF COMPOSITE POLYMER FILMS ON NON-CONDUCTING SUBSTRATES, INCLUDING BANDAGES, AND THEIR USE FOR TREATING WOUNDS

Technology DescriptionResearchers at Johns Hopkins have developed a polymer film coating for bandages and/or medical devices. treating or preventing infections. The coating can be used to delivery drugs for the treatment or prevention of infections, as the material can be synthesized to include several bioactive agents immobilized in such a way that...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Lloyd Miller, Alyssa Ashbaugh, Xuesong Jiang, Jesse Zheng, Sashank Reddy, Bartlomiej Kachniarz

Keywords(s): Bacterial Infections, Disease Indication, Drug Delivery Device, Implanted Device, Implants, Infectious Diseases, Medical Devices, Therapeutic Devices

Category(s): Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

Nerve-sparing Surgical Guidance Using Neuromodulation-based Nerve Localization

Unmet NeedGlobally, prostate cancer is the second leading cause of cancer and the sixth leading cause of cancer-related death in men. In the U.S., prostate cancer is the most common and diagnosed cancer in males. It is estimated there are 2.5 million men living with prostate cancer in the US, and the number is on the rise. The survival of prostate...

Published: 3/14/2025 | Inventor(s): Emad Boctor, Jeeun Kang, Arthur Burnett, Jin Kang, Maged Harraz

Keywords(s): Disease Indication, Erectile Dysfunction (ED), Imaging and Sensing Systems, Imaging Modality, Implanted Device, Implants, In Vivo Medical Imaging, Integrated Imaging System, Integrated Robotic and Imaging System, Interventional and Surgical Systems, Men's Health, Neuromodulator, Surgical Navigation, Therapeutic Devices, Therapeutics, Ultrasound (US)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Men's Health

Initial Proof-of-Concept of Photoacoustic Neural Stimulation; A Potential Approach to Retinal Stimulation: Preliminary In Vitro Study

Unmet NeedNon-cataract related vision loss affects 22.9 million people worldwide. Many of these patients retain partial functionality in their retinas; even though their outer retinas no longer function, visual stimulation can be achieved by sending messages from the inner retinas through the optic nerves. Present efforts to restore vision to these...

Published: 3/13/2025 | Inventor(s): Emad Boctor, James Spicer, Peter Gehlbach, Jeeun Kang, Maged Harraz

Keywords(s): Disease Indication, Environmental Sensing, Eye Disorders, Imaging and Sensing Systems, Implanted Device, Implants, Neuromodulator, Photodetector, Sensors, Signal Display Software, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Industrial Tech > Energy, Infrastructure & Environment, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Industrial Tech, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices > Neurostimulation

Targeting Interleukin 17 and Senescent Cells for Treatment of the Foreign Body Response

Unmet Need13 million medical devices are implanted annually in the United States. Synthetic biomaterials are the building blocks of these implanted devices. Although biomaterials are selected for durability and minimal host immune response, all implanted biomaterials induce the foreign body response (FBR) to some degree, which creates a capsule of fibrous...

Published: 3/14/2025 | Inventor(s): Jennifer Elisseeff, Drew Pardoll, Franck Housseau, Liam Chung

Keywords(s): Antagonists/Inhibitors, Implants, Small Molecules, Target, Therapeutic Devices, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Traumatic Injury, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Medical Devices > Prosthetics

Minimally Invasive Magnetic Vocal Fold Manipulator

Unmet NeedVocal cord paralysis results in a compromised airway, hindering speaking and breathing. To alleviate the effects of paralysis, surgical operations can manipulate the position of the vocal cords by moving them to the side (lateralization) or center (medialization) of the airway. Current state of the art procedures achieve vocal cord lateralization...

Published: 3/14/2025 | Inventor(s): Charles Cummings, Allen Feng, Christopher Razavi, Alexander Hillel

Keywords(s): Disease Indication, Implanted Device, Implants, Speech Disorders, Therapeutic Devices, Therapeutics, Vocal Chord Dysfunction

Category(s): Clinical and Disease Specializations > Speech Disorders > Vocal Chord Dysfunction

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