Search Results - albert+jun

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Alpha 2 Collagen VIII (Col8a2) Q455K Knock-in Mouse Model of Fuchs Endothelial Corneal Dystrophy

Unmet Need:Fuchs’ endothelial corneal dystrophy (FECD) is a genetic disease affecting the cornea and is estimated to affect 7% of the adult population (see Aiello et al. 2022). The first genetic defect shown to cause FECD was a point mutation in the alpha 2 collagen 8 gene (Col8a2). The disease results in a buildup of fluid in the cornea and causes...

Published: 3/13/2025 | Inventor(s): Albert Jun

Keywords(s): Basic Research Biomarker, Cell Lines, Corneal Dystrophy, Discovery/Research Tools, Disease Indication, Eye Disorders, Fuchs' Endothelial Corneal Dystrophy, Fuchs Endothelial Corneal Dystrophy (FECD), In Vitro Research Tool, Mouse Cell Lines

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Research Tools, Clinical and Disease Specializations > Ophthalmology > Corneal Dystrophy, Clinical and Disease Specializations > Ophthalmology > Fuchs' Endothelial Corneal Dystrophy

Hammerhead Irrigation + Aspiration Tip for Cataract Surgery

Unmet NeedCataracts are the leading cause of blindness in the world, accounting for half of blindness cases and affecting about 20 million people. While cataract surgery is an effective procedure for restoring vision with a high success rate, it is a somewhat difficult procedure. Thus, there may be a need for improved surgical tools that make the procedure...

Published: 3/14/2025 | Inventor(s): Albert Jun, Joaquin De Rojas, Jan McGlumphy, Todd Richmond

Keywords(s): Disease Indication, Eye Disorders, Interventional and Surgical Systems, Irrigation/Drainage Tools, Surgical Instruments

Category(s): Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Ophthalmology

Implantable lens capsule for intraocular lens insertion.

Unmet NeedCataract surgery is the most common intraocular surgery, with more than 3.5 million occurring each year in the U.S. Various circumstances compromise the ability to safely insert an intraocular lens (IOL) implant following cataract extraction such as zonular insufficiency or posterior capsule rupture. Alternatives for IOL placement within the...

Published: 3/13/2025 | Inventor(s): Albert Jun, Angela Zhu, Peter Gehlbach

Keywords(s): Disease Indication, Eye Disorders, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

LACRIMAL CANALICULAR DELIVERY SYSTEM AND METHODS OF USE

Unmet NeedThere has been a growing development of novel drug delivery implants and tear drainage occlusion devices designed for delivery in the canalicular space. These implants are delivered through the punctal os, or the entrance to the lacrimal canicular space. These current strategies require the end user to manually insert the introducer at the...

Published: 3/14/2025 | Inventor(s): Bradley Barnett, Albert Jun

Keywords(s): Disease Indication, Drug Delivery Device, Dry Eye Syndrome, Eye Disorders, Glaucoma, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations > Ophthalmology > Glaucoma, Clinical and Disease Specializations > Ophthalmology > Dry Eye Syndrome, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

Helix Reversible Lacrimal Canalicular Occlusion Device and Associated Materials and Methods for Delivery and Recovery

Unmet NeedPatients with dry eye currently get a treatment called Punctal Occlusion. This procedure consists of inserting punctal plugs into the tear drainage area of the eye to keep the tears in the eyes longer. Dry eye syndrome affects between 7.4% and 33.7% of the population. Current solutions are permanent punctal occlusion devices, in which they...

Published: 3/14/2025 | Inventor(s): Albert Jun, Bradley Barnett

Keywords(s): Catheters, Closure/Sealing Devices, Disease Indication, Dry Eye Syndrome, Eye Disorders, Interventional and Surgical Systems, Surgical Instruments, Surgical Tubing

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Ophthalmology > Dry Eye Syndrome

Alpha 2 Collagen VIII (Col8a2) L450W Knock-in Mouse Model of Fuchs Endothelial Corneal Dystrophy

Alpha 2 Collagen VIII (Col8a2) L450W Knock-in Mouse Model of Fuchs Endothelial Corneal DystrophyJHU REF: C13003Invention novelty: This tangible material is an Alpha 2 collagen VIII (Col8a2) L450W knock-in mouse model of Fuchs endothelial corneal dystrophy (FECD)Value PropositionFuchs endothelial corneal dystrophy (FECD) is a progressive, hereditary...

Published: 3/13/2025 | Inventor(s): Albert Jun

Keywords(s): Basic Research Biomarker, Corneal Dystrophy, Discovery/Research Tools, Disease Indication, Eye Disorders, Fuchs' Endothelial Corneal Dystrophy, Fuchs Endothelial Corneal Dystrophy (FECD), In Vivo Research Tool, Knock In Mouse Model, Mouse Model

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology > Corneal Dystrophy, Clinical and Disease Specializations > Ophthalmology > Fuchs' Endothelial Corneal Dystrophy, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Research Tools