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Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses

Safe DC Stimulator for Neural ProsthesesJHU Ref #: [C11822] Unmet NeedCurrently, neural prostheses are limited because they excite neurons but cannot efficiently inhibit them. Direct current (DC) can excite, inhibit, or control extracellular potential of target neurons, but DC stimulation is biologically unsafe. The current solution is to direct DC...

Published: 3/13/2025 | Inventor(s): Charles Della Santina, Gene Fridman

Keywords(s): CNS and Neurological Disorders, Disease Indication, Neuroprosthetic Sensing Algorithms, Neuroprosthetics, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices

Novel Functional Skin Coating Polymer for Robust and Sustained Ultraviolet Protection

Unmet NeedAccording to the WHO, excessive exposure to the sun can lead to cancer, cataracts, other eye diseases as well as visual ageing (WHO). The skin is the ultimate barrier that humans interface with the environment. Unfortunately, the environment we live in is becoming progressively more hostile to our health. Air pollutants (eg., ozone, particulate...

Published: 3/14/2025 | Inventor(s): Sewon Kang, Adam Freeman

Keywords(s): Industrial Manufacturing, Novel Materials, Other, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Engineering Tech > Materials

Smart Ankle Bracelet for Monitoring Limb Perfusion

Unmet NeedPerfusion is the method in which blood is delivered to tissue in animals. All animal tissues require adequate supplies of blood for sustained health and life. However, there are many surgeries and procedures that can decrease adequate perfusion. For example, critical limb ischemia (CLI), which affects more than 2 million people in the United...

Published: 3/14/2025 | Inventor(s): Andrew Schulick, Luke Marone

Keywords(s): Disease Indication, Orthotics, Skeletal Disorders, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Orthopedic Devices

Shingled Aortic Stent Graft

Unmet NeedAortic aneurysms were the cause of almost 10,000 deaths in 2017, and currently have an incidence of 10 cases per 100,000 in the United States. Aortic aneurysms that involve larger vessels pose extremely challenging problems for vascular surgeons. Almost all the vessels that branch out from the aneurysm will require revascularization, but it...

Published: 3/13/2025 | Inventor(s): Andrew Schulick, Devika Singh

Keywords(s): Cardiovascular Diseases, Disease Indication, Implanted Device, Implants, Stent, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular

Targeted Compression Stockings

Unmet NeedMore than 23% of all adults are thought to be affected by varicose veins. These veins are enlarged and swollen as a result of faulty valves that allow blood to flow in the wrong direction. Currently, varicose veins are managed through the application of a compression garment such as a stocking. The garments help prevent veins from being engorged...

Published: 3/13/2025 | Inventor(s): Andrew Schulick, Devika Singh

Keywords(s): Cardiovascular Diseases, Disease Indication, Other, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Cardiovascular

Cell Impregnated Nanofiber Stent Sleeve ("CINSS") for Intravascular Growth Factor Production

Invention novelty:Stem cells are harnessed to create a stent-based “paracrine factor factory” using a novel biodegradable nanofiber sleeve which protects the cells from washout and immune attack, and provides a sheltered in vivo on-stent milieu for the cells to continuously produce and deliver healing growth factors and exosomes to injured tissue.Value...

Published: 3/13/2025 | Inventor(s): Chao-Wei Hwang, Zhiyong Xia, Virginia Bogdan, Jeffrey Brinker, Gary Gerstenblith, Peter Johnston, Steven Schulman, Gordon Tomaselli, Robert Weiss

Keywords(s): Drug Delivery Vehicle, Hydrogel, Implanted Device, Implants, Stent, Therapeutic Devices, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities

Artificial Corneal Device

Unmet NeedCorneal blindness affects an estimated 10 million people worldwide, particularly prevalent in the underdeveloped world. Currently, only about 10% of patients receive a corneal transplant due to a shortage of human donor corneas and difficulty in preserving the tissues. Meanwhile, even in countries with a sufficient donor supply, some patients...

Published: 3/14/2025 | Inventor(s): Esen Akpek, Gopalan Balaji, Thomas Schmiedel, Anuraag Singh

Keywords(s): Carriers/Appliers, Disease Indication, Eye Disorders, Implantation Method, Implants, Interventional and Surgical Systems, Surgical Instruments, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Ophthalmology

Implantable lens capsule for intraocular lens insertion.

Unmet NeedCataract surgery is the most common intraocular surgery, with more than 3.5 million occurring each year in the U.S. Various circumstances compromise the ability to safely insert an intraocular lens (IOL) implant following cataract extraction such as zonular insufficiency or posterior capsule rupture. Alternatives for IOL placement within the...

Published: 3/13/2025 | Inventor(s): Albert Jun, Angela Zhu, Peter Gehlbach

Keywords(s): Disease Indication, Eye Disorders, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

Safe Direct Current Stimulator Design for Reduced Power and Increased Reliability

Unmet NeedNeuroprostheses, such as cochlear implants and neural pacemakers, have already been proven to be useful in varying applications. Current neuroprostheses tools typically employ biphasic pulsatile stimulation, a process where electrodes have both a cathodic phase and an anodic phase to pass charge in both directions. Direct current (DC) has...

Published: 3/13/2025 | Inventor(s): Gene Fridman

Keywords(s): CNS and Neurological Disorders, Computer and Network Systems, Computer Hardware, Disease Indication, Implanted Device, Implants, Neuromodulator, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

COMPOSITIONS AND METHODS FOR PREPARATION OF COMPOSITE POLYMER FILMS ON NON-CONDUCTING SUBSTRATES, INCLUDING BANDAGES, AND THEIR USE FOR TREATING WOUNDS

Technology DescriptionResearchers at Johns Hopkins have developed a polymer film coating for bandages and/or medical devices. treating or preventing infections. The coating can be used to delivery drugs for the treatment or prevention of infections, as the material can be synthesized to include several bioactive agents immobilized in such a way that...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Lloyd Miller, Alyssa Ashbaugh, Xuesong Jiang, Jesse Zheng, Sashank Reddy, Bartlomiej Kachniarz

Keywords(s): Bacterial Infections, Disease Indication, Drug Delivery Device, Implanted Device, Implants, Infectious Diseases, Medical Devices, Therapeutic Devices

Category(s): Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

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