Search Results - peter+johnston

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Non-invasive Left Ventricular End Diastolic Pressure (LVEDP) Measurement for In-hospital, Outpatient and Home Diagnostic Monitoring

Unmet NeedBoth physicians and surgeons rely heavily on the cardiac chamber pressures, especially that in the left ventricle, to assess the fluid volume status of patients and heart function pre and post procedures in the in-hospital setting, outpatient clinics or when patients are at their home. Current methodologies are either invasive in nature with...

Published: 6/27/2024 | Inventor(s): Soumyadipta Acharya, Nichaluk Leartprapun, Qian Liu, Jackline Wanjala, Brian Bernier, Trent Langston, Viachaslau Barodka, David Kass, Majd AlGhatrif, Umang Anand, Chao-Wei Hwang, Peter Johnston, Andrew Bicek

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics

Cell Impregnated Nanofiber Stent Sleeve ("CINSS") for Intravascular Growth Factor Production

Invention novelty:Stem cells are harnessed to create a stent-based “paracrine factor factory” using a novel biodegradable nanofiber sleeve which protects the cells from washout and immune attack, and provides a sheltered in vivo on-stent milieu for the cells to continuously produce and deliver healing growth factors and exosomes to injured tissue.Value...

Published: 6/27/2024 | Inventor(s): Chao-Wei Hwang, Zhiyong Xia, Virginia Bogdan, Jeffrey Brinker, Gary Gerstenblith, Peter Johnston, Steven Schulman, Gordon Tomaselli, Robert Weiss

Keywords(s): Drug Delivery Vehicle, Hydrogel, Implanted Device, Implants, Stent, Therapeutic Devices, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities

An Oscillatory Atherectomy Device Incorporating a Novel Burr Design and Torque Limiting System for the Safer Treatment of Advanced Coronary Artery Disease

Unmet NeedCardiovascular disease is the leadind cause of death globally and the most significant cost contributor to the health care system. When coronary plaques become heavily calcified - which is typical in older patients with long-standing coronary disease and those with co-morbidities such as chronic kidney disease - the compliance of the vessel...

Published: 6/27/2024 | Inventor(s): Caitlin Romanczyk, Peter Johnston, Chao-Wei Hwang, George Coles, Clayton Andrews, Joshua Punnoose, Quinn Salditch, Scott Sterrett, Zachary Buono, Paige Frank, Ananya Gupta

Keywords(s): Atherosclerosis, Cardiovascular Diseases, Disease Indication, Interventional and Surgical Systems, Irrigation/Drainage Tools, Mechanical Cutters/Incision Tools, Surgical Instruments, Vascular Diseases

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Atherosclerosis, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices

Implantable Bioreactor with a Non-Static Cell Pouch

UNMET NEED Heart failure after myocardial infarction (MI) is a common and morbid condition that affects millions worldwide. While there are multiple therapies that help the heart adapt and compensate for the damage incurred in an MI, there remains no method by which injured heart muscle may be repaired or replaced. Stem cell therapy shows great promise...

Published: 6/27/2024 | Inventor(s): Chao-Wei Hwang, Gary Gerstenblith, Peter Johnston, Robert Weiss, Gordon Tomaselli, Steven Schulman

Keywords(s): Cardiovascular Diseases, Cell Therapy, Disease Indication, Implanted Device, Implants, Myocardial Infarction (MI), Single, Therapeutic Devices, Therapeutic Matter, Therapeutic Substance Synthesis Method, Therapeutics, Therapy Type, Tissue Engineering/Regenerative Devices

Category(s): Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction

Implantable Bioreactor for Delivery of Paracrine Factors

C11231 Implantable Bioreactor for Delivery of Paracrine FactorsBackground Intracoronary infusion and intra-myocardial injection of stem cells are believed to improve cardiac function after a heart attack by enhancing repair of damaged...

Published: 6/27/2024 | Inventor(s): Gary Gerstenblith, Chao-Wei Hwang, Peter Johnston, Gordon Tomaselli, Jeffrey Brinker, Robert Weiss, Jason Benkoski, George Coles, Steven Schulman

Keywords(s): Drug Delivery Device, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

Methods to Accelerate Healing of Injured Tissues via Stem Cells in Nanofiber Patches

C12353: Stem Cell Developed Patches for Accelerated AngiogenesisNovelty: This technology describes compositions and methods of use of certain patches, with infused stem cells and/or derived growth factors, used for accelerated healing of tissue injuries.Value Proposition: Existing therapeutic angiogenesis techniques that employ individual growth factors...

Published: 6/27/2024 | Inventor(s): Xiomara Calderon-Colon, Zhiyong Xia, Chao-Wei Hwang, Peter Johnston, Virginia Bogdan

Keywords(s): Disease Indication, Implanted Device, Implants, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Stem Cells, Technology Classifications > Medical Devices