Search Results - george+coles

8 Results

Sort By:

Systems and Methods for Automatic Detection and Localization of Foreign Body Objects during (and after) Neurosurgery

Unmet Need· Retained foreign bodies (RFBs) are remnant materials following neurosurgery, often imperceptible cotton tufts, that can lead to neurological impairment and textilomas (Bechtold et al 2020). The incidence is estimated to be as high as 1 in 100 operations, and cost hospitals millions in healthcare costs and litigation (Whang et al....

Published: 3/14/2025 | Inventor(s): Amir Manbachi, Haley Abramson, Judy Huang, Henry Brem, Nicholas Theodore, George Coles

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Surgery, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Surgical, Technology Classifications > Computers, Electronics & Software > Machine Learning

Low Cost Manual Cataract Fragmentation Device for Improved Access and Outcomes

Unmet Need / Invention Novelty: 17 M people are blind and 83.5 M have moderate-to-severe visual impairment due to cataracts, which disproportionately affect individuals in low- and middle-income countries (LMICs). The current gold standard, phacoemulsification, requires significant initial capital expense and equipment and recurring costs for consumables...

Published: 3/14/2025 | Inventor(s): Kunal Parikh, Namratha Potharaj, Nicholas Calafat, Daniel Myers, Brittany Reed, Krithik Srithar, Samuel Yiu, George Coles, Kapil Mishra, Nakul Shekhawat, Joshua De Souza

Keywords(s):

Category(s): Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Medical Devices

Novel Cardiac Implants and Associated Catheter Systems to Treat Malfunctioning Cardiac Valves

Unmet NeedA common heart disorder seen in thousands of patients per year is regurgitation, a condition where the heart’s valves do not close sufficiently during systolic contraction, allowing for blood to leak from the ventricle into the atrium. This leakage varies from moderate to severe, and at high levels can put the patient at risk of many other...

Published: 3/13/2025 | Inventor(s): Ramji Rengarajan, Kenton Zehr, Todd Crawford, Victor Yu, George Coles, James Beaty, Keith Bulkin, Joseph Walters, Timothy Harrigan, Reggie Roth, James Cawthra, Dennis Werner, Jason Kilvington, Umang Anand, Kalyna Sconzert, Tom Jancaric

Keywords(s): Cardiovascular Diseases, Catheters, Disease Indication, Implantation Method, Implants, Interventional and Surgical Systems, Surgical Instruments, Surgical Tubing, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

An Oscillatory Atherectomy Device Incorporating a Novel Burr Design and Torque Limiting System for the Safer Treatment of Advanced Coronary Artery Disease

Unmet NeedCardiovascular disease is the leadind cause of death globally and the most significant cost contributor to the health care system. When coronary plaques become heavily calcified - which is typical in older patients with long-standing coronary disease and those with co-morbidities such as chronic kidney disease - the compliance of the vessel...

Published: 3/13/2025 | Inventor(s): Caitlin Romanczyk, Peter Johnston, Chao-Wei Hwang, George Coles, Clayton Andrews, Joshua Punnoose, Quinn Salditch, Scott Sterrett, Zachary Buono, Paige Frank, Ananya Gupta

Keywords(s): Atherosclerosis, Cardiovascular Diseases, Disease Indication, Interventional and Surgical Systems, Irrigation/Drainage Tools, Mechanical Cutters/Incision Tools, Surgical Instruments, Vascular Diseases

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Atherosclerosis, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices

A Device and Method to Treat Esophageal Disorders

Unmet needAn effective yet convenient method to treat esophageal disorders does not exist. For example, there is pressing need for non-invasive therapeutic options for patients with Barrett’s esophagus which progresses to low-grade dysplasia or high grade dysplasia. Technology OverviewJohns Hopkins researchers developed devices and methods to administer...

Published: 3/13/2025 | Inventor(s): Florin Selaru, Stephen Meltzer, George Coles, Honggang Cui

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Interventional and Surgical Systems

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology

Atrial Septal Aneurysm Transseptal Access System (ASATAS)

Novel Sheath Designs in a Transseptal Access SystemJHU REF: C12321 Invention Novelty: This technology comprises of a novel sheath design and a transseptal access system for performing transseptal punctures during invasive cardiac procedures. Value Proposition: Transseptal punctures are required to be performed in various invasive cardiac procedures....

Published: 3/13/2025 | Inventor(s): George Coles, Alan Cheng

Keywords(s): Atrial Septal Aneurysm, Cardiovascular Diseases, Catheters, Disease Indication, Interventional and Surgical Systems, Surgical Instruments, Surgical Tubing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Atrial Septal Aneurysm, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices

Implantable Bioreactor for Delivery of Paracrine Factors

C11231 Implantable Bioreactor for Delivery of Paracrine FactorsBackground Intracoronary infusion and intra-myocardial injection of stem cells are believed to improve cardiac function after a heart attack by enhancing repair of damaged...

Published: 3/13/2025 | Inventor(s): Gary Gerstenblith, Chao-Wei Hwang, Peter Johnston, Gordon Tomaselli, Jeffrey Brinker, Robert Weiss, Jason Benkoski, George Coles, Steven Schulman

Keywords(s): Drug Delivery Device, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

Middle Ear Implant Sensor

C12346: Middle Ear Implant SensorNovelty: A piezoelectric sensor for monitoring compressive load and verifying proper sound conduction in middle ear implants to provide surgeons with real-time feedback regarding implant fit and positioning during surgery.Value Proposition: According to the World Health Organization, global incidence of middle ear-related...

Published: 3/13/2025 | Inventor(s): David Kitchin, Dawnielle Farrar-Gaines, George Coles, Howard Francis, Ioan Lina

Keywords(s): Disease Indication, Ear and Hearing Disorders, Prosthetic Feedback Systems, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Ear, Nose & Throat > Hearing Disorders