Search Results - esophageal+cancer

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Diffractive Tethered OCT Capsule Endoscope for Ultrahigh-resolution Imaging

Unmet Need:Optical coherence tomography (OCT) is a noninvasive, high-resolution optical imaging technology capable of real-time imaging of tissue microanatomy. OCT essentially functions as a form of “optical biopsy”, capable of assessing tissue microanatomy and function with a resolution similar to standard histology but without the need for tissue...

Published: 6/27/2024 | Inventor(s): Xingde Li

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Imaging and Sensing Systems, Imaging Probe/Transducer, In Vivo Medical Imaging, Integrated Imaging System

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Esophageal Cancer

A Device and Method to Treat Esophageal Disorders

Unmet needAn effective yet convenient method to treat esophageal disorders does not exist. For example, there is pressing need for non-invasive therapeutic options for patients with Barrett’s esophagus which progresses to low-grade dysplasia or high grade dysplasia. Technology OverviewJohns Hopkins researchers developed devices and methods to administer...

Published: 6/27/2024 | Inventor(s): Florin Selaru, Stephen Meltzer, George Coles, Honggang Cui

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Interventional and Surgical Systems

Endoscopic Abrasion Device

The present invention provides an endoscopic abrasion device and methods of use thereof. The device includes a catheter having an inflation balloon including one or more elements disposed on the balloon for abrasion of tissue when the balloon is rotated about the longitudinal axis of the catheter. The device may be used to treat and diagnose diseases...

Published: 6/27/2024 | Inventor(s): Mouen Khashab, Anthony Kalloo

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Interventional and Surgical Systems, Surgical Instruments

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology

JH-ESO-Ad1

C10511: JH-EsoAd1- Esophageal Cancer Cell Line Technical Details: Esophageal adenocarcinoma currently has one of the most rapidly increasing tumor incidences in the United States, with the vast majority of cases occurring on the backdrop of metaplastic epithelium (Barrett esophagus). The availability of appropriate cell line models is essential...

Published: 6/27/2024 | Inventor(s): James Eshleman

Keywords(s): Basic Research Biomarker, Cancer Cells, Cancers, Cell Lines, Cell Model, Discovery/Research Tools, Disease Indication, Esophageal Cancer, Human Cell Lines, In Vitro Research Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools

Specific Delivery of a Tumor-ablating Agent by a DECApeptide to Colon and Esophageal Cancer Cell Lines as a Therapeutic Treatment

C10039: Specific Delivery of a Tumor-ablating Agent by a DECApeptide to Colon and Esophageal Cancer Cell Lines as a Therapeutic TreatmentValue Proposition: The effectiveness of immunotherapeutic antibodies is limited by their relatively large size. This attribute results in the antibody attachment being limited to the exposed areas of a solid tumor....

Published: 6/27/2024 | Inventor(s): Stephen Meltzer, John Abraham

Keywords(s): Biologics, Cancers, Colorectal Cancer, Disease Indication, Esophageal Cancer, Peptide, Single, Small Molecules, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities

DEC1 KO Lines for Drug Discovery

C04656: DEC1 KO Lines for Drug Discovery Technical Details: Deleted in esophageal cancer 1 (DEC1) gene knockouts of the human keratinocyte cell line, HaCaT. Details are described in the paper by Zawel et al., 2002 Looking for Partners: The cell lines described in this invention can be used in screens for novel molecules that target...

Published: 6/27/2024 | Inventor(s): Kenneth Kinzler, Leigh Zawel, Shibin Zhou, Bert Vogelstein

Keywords(s): Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, Esophageal Cancer, Human Cell Lines, In Vitro Research Tool, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools