Search Results - xingde+li

6 Results

Sort By:

Large-scale Epigenomic Reprogramming Links Anabolic Glucose Metabolism to Distant Metastasis during the Evolution of Pancreatic Cancer Progression

Unmet NeedPancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer death in the western world by 2020. Subclonal populations that emerge and drive metastatic progression of the disease are associated with high mortality rates among patients. Blocking the tumorigenic potential of metastatic sites is key to improving...

Published: 9/26/2024 | Inventor(s): Andrew Feinberg, Xin Li, Christine Iacobuzio-Donahue, Oliver McDonald

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Pancreatic Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Pancreatic Cancer

Detection of Low Abundant Molecules in Complex Mixture

Invention novelty: a method for quantitative, high-throughput analysis of glycans from tissue sections Value PropositionStudies on protein glycosylation have been complicated by the diverse structure of protein glycans and the lack of effective tools to identify the protein glycosylation site and glycan structure. Currently, mass spectrometry is the...

Published: 9/26/2024 | Inventor(s): Xingde Li, Shadi Eshghi, Hui Zhang

Keywords(s): Discovery/Research Tools, In Vitro Research Tool, Research Instrument

Category(s): Technology Classifications > Research Tools

Quantitative Tissue Property Mapping for Real-time Tumor Detection and Interventional Guidance

AbstractReal-Time, Interventional Guidance for Tumor Detection and ExcisionJHU REF: C12934 Invention Novelty: A novel optical method for the identification and differentiation of tumor versus non-tumor tissue with direct visual cue for use in real-time, continuous and noninvasive guidance for tumor excision. Value Proposition: Approximately 13,000 brain...

Published: 9/26/2024 | Inventor(s): Jiefeng Xi, Alfredo Quinones-Hinojosa, Elliott Mcveigh, Kaisorn Chaichana, Carmen Kut, Xingde Li

Keywords(s): Cancers, Disease Indication, Image Processing Software, Image Reconstruction Software, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Interventional and Surgical Systems, Optical Coherence Tomography (OCT), Surgical Navigation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices

Diffractive Tethered OCT Capsule Endoscope for Ultrahigh-resolution Imaging

Unmet Need:Optical coherence tomography (OCT) is a noninvasive, high-resolution optical imaging technology capable of real-time imaging of tissue microanatomy. OCT essentially functions as a form of “optical biopsy”, capable of assessing tissue microanatomy and function with a resolution similar to standard histology but without the need for tissue...

Published: 9/26/2024 | Inventor(s): Xingde Li

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Imaging and Sensing Systems, Imaging Probe/Transducer, In Vivo Medical Imaging, Integrated Imaging System

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Esophageal Cancer

Fiber-optic Methods and Devices Enabling Multiphoton Imaging with Improved Signal-to-Noise Ratio

We report the development of a single-fiber based scanning device (termed as endomicroscope) and system capable of performing high-resolution optical imaging of biological tissues with multiphoton excitation. The imaging device is fiber-optically based and is flexible with a small footprint (~2 mm in diameter), and the entire imaging system is compact...

Published: 9/26/2024 | Inventor(s): Xingde Li, Yicong Wu, Wenxuan Liang

Keywords(s): Image Display Hardware, Image Display Software, Image Processing Hardware, Image Processing Software, Imaging and Sensing Systems, Imaging Modality, Imaging Probe/Transducer, In Vivo Medical Imaging, Integrated Imaging System, Multi-photon Microscopy

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Methods for Color Corrected OCT Imaging Endoscope/Catheter to Achieve High-resolution

C12701 Novel Ultrahigh Resolution Optical Coherence Tomography Endoscopy ProbeInvention Novelty: This invention is a novel optical coherence tomography (OCT) system that improves the image resolution of endoscopy probes in a cost-effective manner. Value Proposition: OCT is a relatively new diagnostic modality that allows a physician to view micrometer...

Published: 9/26/2024 | Inventor(s): Xingde Li, Jiefeng Xi, Anqi Zhang

Keywords(s): Environmental Sensing, Imaging and Sensing Systems, Imaging Probe/Transducer, Interventional and Surgical Systems, Sensors, Surgical Navigation

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics > Diagnostic Imaging