Search Results - hui+zhang

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Detection of Low Abundant Molecules in Complex Mixture

Invention novelty: a method for quantitative, high-throughput analysis of glycans from tissue sections Value PropositionStudies on protein glycosylation have been complicated by the diverse structure of protein glycans and the lack of effective tools to identify the protein glycosylation site and glycan structure. Currently, mass spectrometry is the...

Published: 9/26/2024 | Inventor(s): Xingde Li, Shadi Eshghi, Hui Zhang

Keywords(s): Discovery/Research Tools, In Vitro Research Tool, Research Instrument

Category(s): Technology Classifications > Research Tools

Urinary Glycoproteins for the Early Detection of Aggressive Prostate Cancer

Unmet NeedAccording to the American Cancer Society, prostate cancer is one of the most commonly diagnosed cancers and is the second leading cause of cancer death in men. However, most patients with prostate cancer have the low-risk, nonaggressive form that does not require invasive intervention or treatment. The gold standard of diagnosing men with...

Published: 9/27/2024 | Inventor(s): Hui Zhang, Mingming Dong, Tung-Shing Lih

Keywords(s): Assay, Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics (Old), Prostate Cancer

Category(s): Technology Classifications > Diagnostics > Prognostic Biomarkers, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Diagnostics > In Vitro Diagnostics

Detection of Prostate Cancer Proteins in Serum for Cancer Diagnosis with a Blood Test

There is a crucial need of discovering novel biomarkers in addition to prostate specific antigen (PSA) to improve the specificity of clinical diagnosis for prostate cancer. This invention addresses this problem by discovering proteins from prostate cancer tissues that can be detected in patients’ blood. Hence, a blood test can be developed for detecting...

Published: 9/26/2024 | Inventor(s): Yan Li, Daniel Chan, Zhen Zhang, Lori Sokoll, Hui Zhang

Keywords(s): Assay, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Prostate Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology > Prostate Cancer

Integrated Proteomic Biomarkers for the Detection of Aggressive Prostate Cancer

Unmet Need / Invention Novelty: Current prostate-specific antigen (PSA)-based tests lack specificity in differentiating between aggressive and non-aggressive prostate cancer (PC), the latter of which does not require invasive intervention or treatment. Aggressive prostate cancer is therefore over-diagnosed and overtreated. There is an unmet need to...

Published: 9/27/2024 | Inventor(s): Daniel Chan, Zhen Zhang, Lori Sokoll, Jin Song, Shiyong Ma, Hui Zhang

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Diagnostics > Biomarkers

EXoO-Tn Tag-n-Pin the Pan-Carcinoma Tn Antigen in Human Proteome

Unmet NeedAberrant glycosylation has been implicated as a mechanism of cancer progression. Accordingly, identifying the differences in glycan structures within clinical specimens, cancer, and normal cells provides a unique opportunity to identify new biomarkers and therapeutic targets. In particular, Tn antigen (Tn) is a simple O-linked glycan structure...

Published: 9/27/2024 | Inventor(s): Hui Zhang, Weiming Yang

Keywords(s): Analytical Method, Assay, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics (Old), In Vitro Research Tool, Pancreatic Cancer, Pancreatic ductal adenocarcinoma

Category(s): Clinical and Disease Specializations > Oncology > Pancreatic Cancer, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics > Biomarkers

Serum Angiogenic Factors as Prognostic Biomarkers in Prostate Cancer

Novelty:Identification of two diagnostic and prognostic biomarkers whose levels in serum were associated with the presence of aggressive prostate cancer. Value Proposition:Currently, no clear test exists to accurately determine the aggressiveness of prostate cancer. This technology is capable of identifying the aggressiveness of a prostate cancer, leading...

Published: 9/26/2024 | Inventor(s): Danni Li, Daniel Chan, Hui Zhang, Xiangchun Wang

Keywords(s): Assay, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Prostate Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools

Biomarkers for Aggressive Prostate Cancer

C11470: Biomarkers for Aggressive Prostate CancerNovelty: This technology comprises the discovery of novel biomarkers which could be useful for cancer diagnosis and monitoring the treatment of aggressive prostate tumor.Value Proposition: Existing technologies fail to reliably distinguish aggressive prostate cancer from non-aggressive prostate cancer....

Published: 9/26/2024 | Inventor(s): Daniel Chan, Yuan Tian, Jing Chen, Hui Zhang

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Prognostic Biomarker, Prostate Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostics Biomarkers, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology