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Identification and testing of novel methylated markers that distinguish between primary diffuse large B-cell lymphoma of the central nervous system (DBCL-CNS) and other tumors of the CNS

Unmet NeedGlobally, approximately 300,000 brain cancers are diagnosed each year, which results in about 227,000 deaths (Lancet Neurology). Primary central nervous system B-cell lymphomas (PCNSL) are an aggressive and rare disease, which can involve brain, eye or leptomeninges without evidence of systemic disease (Low, S. et al. 2018). A surgical biopsy...

Published: 6/12/2026 | Inventor(s): Bradley Downs, Saraswati Sukumar, Wanjun Ding, WeiPing Tao

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Category(s): Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Biomarkers