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Automatic Radiological Reports and ASPECTS Calculation from Brain MRIs

Unmet NeedThe typical workflow for reporting quantitative data in Picture Archive and Communication System (PACS), is redundant, subjective, time-consuming, and hard to record. Automated radiological reports describing consistent lesion features such as location, contrast, and volumes, and related effects is a time-saver, particularly in acute conditions...

Published: 5/10/2024 | Inventor(s): Andreia Faria, Chin-Fu Liu

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Myelin Protein Zero (MPZ)-targeting Compounds and Uses Thereof

Unmet NeedPeripheral nerve injuries require optimally timed intervention to maximize functional recovery and minimize permanent nerve death and negative impacts to quality of life. Current treatment plans rely primarily on monitoring for spontaneous healing or an indication that there must be surgical intervention, an approach that hinges on accurate...

Published: 5/10/2024 | Inventor(s): Martin Pomper, Catherine Foss, Sami Tuffaha, William Padovano, Bei Cheng

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

A Simplified and More Accessible Method for Production of 111In-XYIMSR for Patient Use

Unmet NeedEach year in the United States, ~82,000 patients are diagnosed with renal cell carcinoma (RCC), and there are ~15,000 RCC-related deaths (1). 75-85% of these cancers are subtyped as clear cell renal cell carcinoma (ccRCC) (2). ccRCC is characterized by overexpression of carbonic anhydrase IX (CAIX) (3). Researchers have previously developed...

Published: 5/10/2024 | Inventor(s): Martin Pomper, Babak Behnam Azad, Robert Dannals, Daniel Holt

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > Diagnostic Imaging, Clinical and Disease Specializations > Oncology > Renal Cell Carcinoma

Compact Capillaroscope for Non-invasive Blood Analysis

Unmet NeedAnalysis of a complete blood count (CBC) test can help detect a plethora of diseases and conditions including leukemia, anemia, and blood infections. The information gained from a CBC analysis helps doctors treat any unusual symptoms, reduce risk of disease or complications, or simply help the patient make decisions to optimize their health....

Published: 5/10/2024 | Inventor(s): Nicholas Durr, Gregory McKay

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Hematology, Technology Classifications > Medical Devices > Imaging

Neuroscore

NeuroscoreJHU Ref #: C17050Technology Description: Researchers at Johns Hopkins University have developed a product that provides a uniform clinical score for Sturge-Weber Syndrome by determining whether cortical atrophy correlates to clinical severity. The clinical severity was evaluated using computer aided analysis of MRIs to produce laterality scores...

Published: 5/10/2024 | Inventor(s): Anne Comi

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Clinical and Disease Specializations > Neurology

Thymosin-based Peptides for Non-invasive Cancer Detection and Targeted Delivery

Unmet Need:Breast cancer is the second most common cancer among women in the US. In 2017, for every 100,000 women, 125 new Female Breast Cancer cases were reported and 20 women died of breast cancer (see CDC, 2020). Currently, mammography is the primary screening approach for breast cancer with limitations such as occult disease as well as breast tissue...

Published: 5/10/2024 | Inventor(s): Babak Behnam Azad

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics > Diagnostic Imaging

Spectral DSA

Unmet NeedCT angiography with digital subtraction (DSA) is the standard diagnostic imaging method for cardiovascular abnormalities (1). This technique captures images both before and after injection of radiopaque contrast; images are then subtracted from one another, leaving only contrast enhanced vasculature in the final image. While DSA is the gold...

Published: 5/10/2024 | Inventor(s): Joseph Stayman, Jianan Gang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Imaging, Clinical and Disease Specializations > Cardiovascular > Aneurysm, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Clinical and Disease Specializations > Neurology > Cerebral Aneurysm, Clinical and Disease Specializations > Neurology > Cerebral Ischemia, Clinical and Disease Specializations > Neurology > Hemorrhage

Non-circular CT Orbit Design for Minimization of Metal Artifacts

Unmet Need· Computed tomography scans (CT) are highly detailed, cross-sectional images that provide critical information for diagnostic and therapeutic purposes (FDA); however, this imaging modality is susceptible to “missing data” due to metal artifacts of implants or other tools (Alzain et al.). Current techniques to overcome these obscured...

Published: 5/9/2024 | Inventor(s): Jianan Gang, Joseph Stayman

Keywords(s): Computer Systems Based on Mathematical Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Distortion Elimination Software, Image Processing Software, Imaging and Sensing Systems, In Vivo Medical Imaging, Physics

Three Material Decomposition using a Triple-Layer Flat-Panel Detector

Value Proposition:Method for direct, real-time visualization of bone, water, and iodine contrast agents.Allows for better visualization of moving structures; reduces imaging artifacts induced by motion (i.e. beating heart) Technology DescriptionResearchers at Johns Hopkins have developed a method for fast processing of data acquired using a triple-layer...

Published: 5/10/2024 | Inventor(s): Joseph Stayman, Jianan Gang, Xiao Jiang

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Computers, Electronics & Software > Machine Learning

A System for the Automated Classification of Disease Tissue in Molecular Imaging Studies utilizing Convolutional Neural Networks with User-Selectable Sensitivity and Specificity

Unmet NeedMedical imaging is an important diagnostic tool used for the detection of a wide array of clinical conditions. The application of Artificial Intelligence (AI) and Deep Learning (DL) is being developed to assist medical imaging professionals manage the ever-growing number of images which they must interpret in their research and clinical practice....

Published: 5/10/2024 | Inventor(s): Jeffrey Leal

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

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