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Compact Capillaroscope for Non-invasive Blood Analysis

Unmet NeedAnalysis of a complete blood count (CBC) test can help detect a plethora of diseases and conditions including leukemia, anemia, and blood infections. The information gained from a CBC analysis helps doctors treat any unusual symptoms, reduce risk of disease or complications, or simply help the patient make decisions to optimize their health....

Published: 5/10/2024 | Inventor(s): Nicholas Durr, Gregory McKay

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Hematology, Technology Classifications > Medical Devices > Imaging

Method to Measure Mechanical Strain in the Optic Nerve Head of Glaucoma Patients

Value Proposition: Non-invasive measurement of glaucoma progression and response to medicationApplicable for use on existing optical coherence tomography (OCT) imaging dataQuantifiable and dynamic biomarker of intraocular pressure-related changes to the eyePatient-specific approach to assess glaucoma risk and progressionTechnology Description: Researchers...

Published: 5/10/2024 | Inventor(s): Thao Nguyen, Harry Quigley, Cameron Czerpak, Vanessa Hannay, Dan Midgett

Keywords(s):

Category(s): Clinical and Disease Specializations > Ophthalmology, Clinical and Disease Specializations > Ophthalmology > Glaucoma, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics

Anti-Human IgG–Invertase Fusion Protein for Quantitative Immunosensing Using Glucometers

Unmet Need / Invention Novelty To mitigate the spread of infectious diseases, rapid and widely available testing methods are needed to screen immunity at the population scale. Current antibody quantification assays often require lab-based instrumentation and methodology that can only be used/followed by skilled personnel. Unfortunately, at-home tests...

Published: 5/10/2024 | Inventor(s): Jamie Spangler, Miguel Aller Pellitero, Boris Juelg, Netzahualcoyotl Arroyo, Elissa Leonard

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics

Non-invasive Left Ventricular End Diastolic Pressure (LVEDP) Measurement for In-hospital, Outpatient and Home Diagnostic Monitoring

Unmet NeedBoth physicians and surgeons rely heavily on the cardiac chamber pressures, especially that in the left ventricle, to assess the fluid volume status of patients and heart function pre and post procedures in the in-hospital setting, outpatient clinics or when patients are at their home. Current methodologies are either invasive in nature with...

Published: 5/9/2024 | Inventor(s): Soumyadipta Acharya, Nichaluk Leartprapun, Qian Liu, Jackline Wanjala, Brian Bernier, Trent Langston, Viachaslau Barodka, David Kass, Majd AlGhatrif, Umang Anand, Chao-Wei Hwang, Peter Johnston, Andrew Bicek

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics

Breast Biopsy Needle Guide

Unmet NeedAround 250,000 patients are diagnosed with breast cancer each year, and overall, 1 in 8 women will be diagnosed with breast cancer in her lifetime. In order for proper diagnosis, biopsies must be performed, usually requiring minor, open surgery. The procedures commence with needle localization, where the radiologist inserts a needle into the...

Published: 5/9/2024 | Inventor(s): Andrew Schulick, Devika Singh

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health

Method to Use Viral and Host Methylation Markers for Cervical Cancer Screening and Triage in Liquid Prep, Serum/plasma, and Urine: PCR and Sequencing Based Process Methods

Novel Method for Cervical Cancer ScreeningJHU REF: C13649Invention novelty: This invention is a diagnostic method for diagnosis and progression monitoring of premalignant lesions in cervical cancer via DNA methylation and quantitative Methylation Specific PCR (qMSP).Value Proposition:Currently, the primary diagnostic for cervical cancer is a Papanicolaou...

Published: 5/9/2024 | Inventor(s): Rafael Guerrero-Preston, David Sidransky

Keywords(s): Biomarker, Clinical Diagnostics, Diagnostic Tool, Disease Indication, Epigenetic, Human Papillomavirus, Human Papillomavirus (HPV), In Vitro Diagnostics (Old), Infectious Diseases, Measurement Tool, Methylation, Viral Infections

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Infectious Diseases > Human Papillomavirus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections

Gene Expression Profile Determination and Prognostication in Uveal Melanoma Using Artificial Intelligence

Prognostication in Uveal Melanoma Using Artificial Intelligence Disclosure Date:12/05/2018 Description: Unmet NeedUveal melanoma is the most common primary intraocular malignancy in adults. According to the University of Michigan W. K. Kellogg Eye Center, there are 5 to 6 uveal melanoma cases per million people per year. For people over the age of 50,...

Published: 5/9/2024 | Inventor(s): Tin Yan Liu, Zelia Correa

Keywords(s): Biopsy Tools, Cancers, Clinical Diagnostics, Computer and Network Systems, Computer Software, Diagnostic Tool, Disease Indication, Image Analysis Software

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence

An Improved Monocular Eye Position Sensor

Unmet Need There is a need for very fast eye position sensors. Video systems are still too slow to be used for eye tracking in many demanding ophthalmologic and neurologic applications. Technical Overview Johns Hopkins faculty members, Dr. Boris Gramatikov and Dr. David Guyton, have invented a novel class of technologies for very fast detection of...

Published: 5/9/2024 | Inventor(s): David Guyton, Boris Gramatikov

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics

An ECL-based Autoantibody Assay for Early Diagnosis of T1D Using a Membrane-spanning ZnT8 Antigenic Domain

Unmet NeedApproximately 1.25 million people in the US have type 1 diabetes (T1D) and the rates of newly diagnosed cases in children are on the rise each year. T1D is caused by the development of an autoimmune reaction to pancreatic β cells. The first detectable sign of β cell autoimmunity is the appearance of diabetes-associated autoantibodies, which...

Published: 5/9/2024 | Inventor(s): Dax Fu, Chengfeng Merriman, Liping Yu, Yong Gu

Keywords(s): Assay, Biomarker, Clinical Diagnostics, Diabetes, Diagnostic Biomarker, Diagnostic Tool, Disease Indication, In Vitro Diagnostics (Old), Measurement Tool, Metabolic Disorders, Type II Diabetes

Category(s): Clinical and Disease Specializations > Diabetes > Type 1 Diabetes, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Diabetes > Type 2 Diabetes, Technology Classifications > Diagnostics > Diagnostic Biomarkers

Method of Computing Low Oxygen Delivery during Cardiac Surgery on Cardiopulmonary Bypass

Technology OverviewThis technology involves a novel algorithm to quantify low oxygen delivery by taking into account not only the depth of oxygen delivery below certain predefined thresholds, but also the time spent below those given thresholds. JHU researchers have preliminary data that assessing oxygen delivery in this manner is associated with release...

Published: 5/9/2024 | Inventor(s): Jonathan Magruder

Keywords(s): Cardiovascular Diseases, Clinical Diagnostics, Computer and Network Systems, Computer Software, Diagnostic Tool, Disease Indication, Measurement Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics > In Vivo Diagnostics

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