Search Results - measurement+tool

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Non-invasive Left Ventricular End Diastolic Pressure (LVEDP) Measurement for In-hospital, Outpatient and Home Diagnostic Monitoring

Unmet NeedBoth physicians and surgeons rely heavily on the cardiac chamber pressures, especially that in the left ventricle, to assess the fluid volume status of patients and heart function pre and post procedures in the in-hospital setting, outpatient clinics or when patients are at their home. Current methodologies are either invasive in nature with...

Published: 5/9/2024 | Inventor(s): Soumyadipta Acharya, Nichaluk Leartprapun, Qian Liu, Jackline Wanjala, Brian Bernier, Trent Langston, Viachaslau Barodka, David Kass, Majd AlGhatrif, Umang Anand, Chao-Wei Hwang, Peter Johnston, Andrew Bicek

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics

Method to Use Viral and Host Methylation Markers for Cervical Cancer Screening and Triage in Liquid Prep, Serum/plasma, and Urine: PCR and Sequencing Based Process Methods

Novel Method for Cervical Cancer ScreeningJHU REF: C13649Invention novelty: This invention is a diagnostic method for diagnosis and progression monitoring of premalignant lesions in cervical cancer via DNA methylation and quantitative Methylation Specific PCR (qMSP).Value Proposition:Currently, the primary diagnostic for cervical cancer is a Papanicolaou...

Published: 5/9/2024 | Inventor(s): Rafael Guerrero-Preston, David Sidransky

Keywords(s): Biomarker, Clinical Diagnostics, Diagnostic Tool, Disease Indication, Epigenetic, Human Papillomavirus, Human Papillomavirus (HPV), In Vitro Diagnostics (Old), Infectious Diseases, Measurement Tool, Methylation, Viral Infections

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Infectious Diseases > Human Papillomavirus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections

An Improved Monocular Eye Position Sensor

Unmet Need There is a need for very fast eye position sensors. Video systems are still too slow to be used for eye tracking in many demanding ophthalmologic and neurologic applications. Technical Overview Johns Hopkins faculty members, Dr. Boris Gramatikov and Dr. David Guyton, have invented a novel class of technologies for very fast detection of...

Published: 5/9/2024 | Inventor(s): David Guyton, Boris Gramatikov

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Diagnostics

Fast and Automatic Periacetabular Osteotomy Fragment Pose Estimation Using Intraoperatively Implanted Fiducials and Single-View Fluoroscopy

Unmet NeedDevelopmental dysplasia of the hip (DDH) is the most common developmental hip deformity in children, and the most common single cause of osteoarthritis of the hip in young and older adults. This condition occurs when there is insufficient coverage of the femoral head by an excessively shallow acetabulum (hip socket). Periacetabular osteotomy...

Published: 5/9/2024 | Inventor(s): Russell Taylor, Robert Grupp, Mehran Armand

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Image Display Software, Image Processing Software, Imaging and Sensing Systems, In Vivo Medical Imaging, Measurement Tool, Pattern Recognition Software

Category(s): Clinical and Disease Specializations > Surgery, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Computers, Electronics & Software > Machine Learning

An ECL-based Autoantibody Assay for Early Diagnosis of T1D Using a Membrane-spanning ZnT8 Antigenic Domain

Unmet NeedApproximately 1.25 million people in the US have type 1 diabetes (T1D) and the rates of newly diagnosed cases in children are on the rise each year. T1D is caused by the development of an autoimmune reaction to pancreatic β cells. The first detectable sign of β cell autoimmunity is the appearance of diabetes-associated autoantibodies, which...

Published: 5/9/2024 | Inventor(s): Dax Fu, Chengfeng Merriman, Liping Yu, Yong Gu

Keywords(s): Assay, Biomarker, Clinical Diagnostics, Diabetes, Diagnostic Biomarker, Diagnostic Tool, Disease Indication, In Vitro Diagnostics (Old), Measurement Tool, Metabolic Disorders, Type II Diabetes

Category(s): Clinical and Disease Specializations > Diabetes > Type 1 Diabetes, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Diabetes > Type 2 Diabetes, Technology Classifications > Diagnostics > Diagnostic Biomarkers

Intraoperative 'non-lifting' Peripheral Nerve Action Potential Recording

Unmet NeedIntraoperative nerve action potential (NAP) is the most common and useful tool for surgeons to guide decisions on surgical approaches during nerve repair surgeries. In a recent trial conducted with 1975 nerves, 57% of the neural elements were completely and perfectly repaired using NAP. Many researchers believe the number of successes would...

Published: 5/9/2024 | Inventor(s): Matthias Ringkamp, Gang Wu, Gene Fridman

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications > Diagnostics

HIV Serosignatures for Cross-sectional Incidence Estimation

Unmet NeedAccording to UNAIDS, there were approximately 36.9 million people worldwide living with HIV/AIDS in 2017. An estimated 1.8 million individuals worldwide became newly infected with HIV in 2017 – about 5,000 new infections per day.Measuring the incidence of HIV in a population is important for improving at-risk populations and intervention...

Published: 5/9/2024 | Inventor(s): Susan Eshleman, Oliver Laeyendecker, Harry Larman, Kai Kammers

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Disease Indication, HIV/AIDS, Infectious Diseases, Measurement Tool

Category(s): Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers

Method for Patient-Specific Decision Support in Spine Surgery

Unmet NeedThe current landscape of spine surgery suffers from unacceptably high variability in outcomes. Undesired events such as revision surgery, failed back surgery, and recurrent lumbar disc herniation are becoming increasingly common. The relationships between patient risk factors and outcomes are complex and poorly understood. Thus, determining...

Published: 5/9/2024 | Inventor(s): Jeffrey Siewerdsen, Nicholas Theodore, Wathudurage De Silva, Satyanarayana Vedula

Keywords(s): Clinical Diagnostics, Computer and Network Systems, Computer Software, Diagnostic Tool, Image Analysis Software, Image Processing Software, Imaging and Sensing Systems, In Vivo Medical Imaging, Measurement Tool, Pattern Recognition Software

Category(s): Clinical and Disease Specializations > Surgery, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Diagnostic Imaging

Method of Computing Low Oxygen Delivery during Cardiac Surgery on Cardiopulmonary Bypass

Technology OverviewThis technology involves a novel algorithm to quantify low oxygen delivery by taking into account not only the depth of oxygen delivery below certain predefined thresholds, but also the time spent below those given thresholds. JHU researchers have preliminary data that assessing oxygen delivery in this manner is associated with release...

Published: 5/9/2024 | Inventor(s): Jonathan Magruder

Keywords(s): Cardiovascular Diseases, Clinical Diagnostics, Computer and Network Systems, Computer Software, Diagnostic Tool, Disease Indication, Measurement Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics > In Vivo Diagnostics

Streamlined Platform for Bacterial Identification and Antimicrobial Susceptibility Test

Unmet NeedFor managing dangerous infections, clinicians need to know what bacteria strain(s) is/are causing the infections, the bacterial loads, and the antibiotic resistance profile of the bacteria. Without knowing this vital information in a timely manner, it is impossible to begin using narrow-spectrum antibiotics that can effectively treat the...

Published: 5/9/2024 | Inventor(s): Tza-Huei (Goes by Jeff) Wang, Pornpat Athamanolap, Liben Chen, Kuangwen Hsieh

Keywords(s): Assay, Bacterial Infections, Clinical Diagnostics, Diagnostic Tool, Disease Indication, In Vitro Diagnostics, Measurement Tool, Microfluidic

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Microfluidics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools

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