Search Results - aleksander+popel

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Mimetic peptides derived from collagen type IV for the treatment of angiogenesis-dependent diseases

C11348: Novel Anti-Angiogenic Collagen Derived Mimetic PeptidesNovelty:modified peptides from collagen IV derived parent peptide Pentastatin-1Value Proposition:The invention describes the synthesis of novel anti-angiogenic by substituting particular amino acids of the peptide Pentastatin-1 derived from collagen IV. Other advantages include:• Ability...

Published: 1/22/2026 | Inventor(s): Niranjan Pandey, Elena Rosca, Corban Rivera, Jacob Koskimaki, Amir Tamiz, Aleksander Popel

Keywords(s): Biologics, Cancers, Disease Indication, Peptide, Protein, Single, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Therapeutic Modalities

Polymeric particles for sustained delivery of multimodal peptide therapeutics

Value Proposition· Stability: polymeric nanoparticle encapsulation increases and sustains peptide residence time, for increased accumulation in tissue vasculature and maximize treatment effects· Safety: use of nanoparticles reduces toxicity by confining peptide delivery to site of administration· Flexible formulation approaches: system's...

Published: 1/22/2026 | Inventor(s): Jordan Green, Aleksander Popel, Joel Sunshine, Ron Shmueli, Stephany Tzeng, Kristen Kozielski

Keywords(s): Biologics, Drug Delivery Vehicle, Nucleic Acid, Peptide, Polymers, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities

Chemokine-derived Peptides that Induce Immunogenic Cancer Cell Death

Value PropositionHigh cancer cell specificity by cell surface characteristics.High water solubility.Combination of oncolytic and anti-angiogenic properties.Unmet NeedThere currently are no peptides reported to have both oncolytic and anti-angiogenic activities. Additionally, drug development requires solubility in water; however, the reported oncolytic...

Published: 1/22/2026 | Inventor(s): Aleksander Popel, Natsuki Furukawa, Niranjan Pandey, Adam Mirando

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Peptides, Technology Classifications > Therapeutic Modalities > Peptides

Peptide Inhibitors or Modifiers of Angiogenesis and Their Applications

C05140: Novel Peptide and Protein Modulators of AngiogenesisNovelty: Identification of families of angiogenesis modulating peptides and development of computational screening methods for the same.Value Proposition: The invention features a list of protein families and certain isolated peptides which have been found to possess angiogenesis modulating...

Published: 1/22/2026 | Inventor(s): Aleksander Popel, Emmanouil Karagiannis

Keywords(s): Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Physics

Category(s): Technology Classifications > Computers, Electronics & Software

Identification of Novel Putative Endogeneous Angiogenic Protein Inhibitors

C04835: Novel Peptide Inhibitors of AngiogenesisNovelty: Identification of 156 novel peptide fragments with putative anti-angiogenic properties.Value Proposition: Anti-angiogenic inhibitors are proving to be a very effective way of targeting a variety of cancers with metastatic potential. This invention features an empirical list of several families...

Published: 1/22/2026 | Inventor(s): Aleksander Popel, Emmanouil Karagiannis

Keywords(s): Biologics, Cancers, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Peptide, Physics, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Therapeutic Modalities > Peptides, Clinical and Disease Specializations > Oncology