Search Results - computer+systems+based+on+specific+computational+models

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Patient-specific simulation guidance of infarct-related ventricular ablation and cardiac resynchronization therapy

Value Proposition· Non-invasive: MRI-based computational modeling provides guidance for catheter-based ablation or LV electrode placement in the treatment of hear disease.· Personalized: Predicts location of optimal ablation or LV electrode placement for each patient.Unmet Need· Ventricular tachycardia (VT) in the setting of myocardial...

Published: 3/13/2025 | Inventor(s): Natalia Trayanova, Henry Halperin, Jason Constantino, Hermenegild Arevalo

Keywords(s): Cardiovascular Diseases, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software

Non-circular CT Orbit Design for Minimization of Metal Artifacts

Unmet Need· Computed tomography scans (CT) are highly detailed, cross-sectional images that provide critical information for diagnostic and therapeutic purposes (FDA); however, this imaging modality is susceptible to “missing data” due to metal artifacts of implants or other tools (Alzain et al.). Current techniques to overcome these obscured...

Published: 3/14/2025 | Inventor(s): Jianan Gang, Joseph Stayman

Keywords(s): Computer Systems Based on Mathematical Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Distortion Elimination Software, Image Processing Software, Imaging and Sensing Systems, In Vivo Medical Imaging, Physics

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Spontaneous Half-quantum Flux Qubit Constructed with Novel Superconducting Materials

Unmet NeedThere is a need for improved quantum computing technology outside the standard superconducting loops where are currently in the process of being developed by a number of major corporations and research institutions. Superconducting loops require extensive cryogenic isolation and have comparably low longevity and logic success rates. In comparison...

Published: 3/14/2025 | Inventor(s): Chia-Ling Chien, Yufan Li, Xiaoying Xu

Keywords(s): Computer and Network Systems, Computer Hardware, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Physics

Category(s): Technology Classifications > Computers, Electronics & Software

Method for Amplifying and Commoditizing Latent Value in Network-Accessible Data Stores

Unmet NeedThe age of technology has allowed data to be stored on devices, servers, or in the cloud. Such a store of data typically arises through the engagement of an individual with one of many kinds of ‘Service Providers’ (SPs) that record data about the individual on a database that the SP operates. This data is exclusive only to the SP and inaccessible...

Published: 3/13/2025 | Inventor(s): Daniel Darg

Keywords(s): Computer Systems Based on Mathematical Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Electrical Digital Data Processing, Physics

Category(s): Technology Classifications > Computers, Electronics & Software

Comprehensive Phenotyping Reveals Robust Determination to Cellular Biological Age

Technology OverviewJHU researchers have developed a platform to determine the cellular biological age of individuals based on quantifiable functional outputs of their cells. Using a comprehensive approach, of high-throughput single cell technologies to measure biochemical and biophysical properties of cells, we have further developed a generalized linear...

Published: 3/13/2025 | Inventor(s): Jude Phillip, Denis Wirtz, Pei-Hsun Wu, Jeremy Walston

Keywords(s): Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Discovery/Research Tools, In Vitro Research Tool, Physics, Research Instrument

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools

Generation of Covariance Sequential Correlation Maps using Spectral Derivatives and Multiplication of Resulting Covariance Matrices

Technology OverviewThe technology consists of a computer script that produces 3D sequential correlation maps involving amide protons and nitrogens from conventional pairs of triple-resonance nuclear magnetic resonance (NMR) spectra. The maps combine the information provided otherwise separately by all spectra. Derivation (gradient) is performed in the...

Published: 3/13/2025 | Inventor(s): Bradley Harden, Dominique Frueh

Keywords(s): Computer Systems Based on Mathematical Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Physics

Category(s): Technology Classifications > Computers, Electronics & Software

A Machine Learning Approach to Beamforming

Unmet NeedGiven their ability to aid in real-time navigation of our complex anatomy, ultrasound and photoacoustic images are popular options for image guidance during surgery. However, noise in these images complicate surgical procedures, particularly noise caused by reflection and reverberation artifacts from highly echogenic structures, which often...

Published: 3/13/2025 | Inventor(s): Muyinatu Bell, Austin Reiter

Keywords(s): Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Imaging and Sensing Systems, In Vivo Medical Imaging, Physics

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis

Using Patient-Specific Modeling of the Heart for Risk Stratification for Ventricular Arrhythmia in Patients with Repaired Tetralogy of Fallot (TOF) via Image-Based Computational Simulations

The JHU inventors previous invention (C11304) provides a non-invasive method to identify the optimal ablation sites for infarct-related ventricular tachycardia (VT) by using 3D electrophysiological heart simulations with a model reconstructed from the patient’s late gadolinium-enhanced (LGE) MRI image. In this application, the inventors extend that...

Published: 3/13/2025 | Inventor(s): Natalia Trayanova, Adityo Prakosa, Mark Cartoski, Patrick Boyle

Keywords(s): Arrhythmias, Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Cardiovascular

SNVBox – UPDATE

Unmet Need In the new “post-genome” era of personalized medicine, many variants critical to disease susceptibilities and drug sensitivities will be identified and increased numbers of people will undergo genetic testing. The Karchin group is developing algorithms and tools to facilitate this process. These models are being applied to cancer genomics,...

Published: 3/13/2025 | Inventor(s): Rachel Karchin, Michael Ryan, Mark Diekhans, Hannah Carter, Christopher Douville, Rick Kim

Keywords(s): Computer and Network Systems, Computer Software, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computer Systems Utilizing Knowledge Based Models, Computing; Calculating; Counting, Data Processing Systems or Methods, Specifically Adapted fo~, Data Processing Systems or Methods, Specifically Adapted for, Electrical Digital Data Processing, Physics

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Financial Tech, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Algorithms

Topology Optimization Software for Linear Elastic Continuum Solid Mechanics

The problem this Topological Optimization Software seeks to address is a problem which humanity has grappled with ever since our ancestors began to make tools - design optimization. This goes beyond the mere shape of an item but can also include what materials the item will be made out of. This optimization process is known as topology. The Topological...

Published: 3/13/2025 | Inventor(s): James Guest

Keywords(s): Computer Systems Based on Mathematical Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Physics

Category(s): Technology Classifications > Computers, Electronics & Software

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